D475-0073 Screening compound: 2-[5-hydroxy-3-methyl-1-(4-phenyl-1,3-thiazol-2-yl)-1H-pyrazol-4-yl]-1-(pyrrolidin-1-yl)ethan-1-one

D475-0073 Screening compound: 2-[5-hydroxy-3-methyl-1-(4-phenyl-1,3-thiazol-2-yl)-1H-pyrazol-4-yl]-1-(pyrrolidin-1-yl)ethan-1-one
D475-0073 Screening compound: 2-[5-hydroxy-3-methyl-1-(4-phenyl-1,3-thiazol-2-yl)-1H-pyrazol-4-yl]-1-(pyrrolidin-1-yl)ethan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound D475-0073
2-[5-hydroxy-3-methyl-1-(4-phenyl-1,3-thiazol-2-yl)-1H-pyrazol-4-yl]-1-(pyrrolidin-1-yl)ethan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D475-0073

Molecular Formula

C19H20N4O2S (C19 H20 N4 O2 S)

Compound Name

2-[5-hydroxy-3-methyl-1-(4-phenyl-1,3-thiazol-2-yl)-1H-pyrazol-4-yl]-1-(pyrrolidin-1-yl)ethan-1-one

IUPAC name

2-[5-hydroxy-3-methyl-1-(4-phenyl-13-thiazol-2-yl)-1H-pyrazol-4-yl]-1-(pyrrolidin-1-yl)ethan-1-one

SMILES

Cc(c(CC(N1CCCC1)=O)c1O)nn1-c1nc(-c2ccccc2)cs1

InChI

InChI=1S/C19H20N4O2S/c1-13-15(11-17(24)22-9-5-6-10-22)18(25)23(21-13)19-20-16(12-26-19)14-7-3-2-4-8-14/h2-4,7-8,12,25H,5-6,9-11H2,1H3

InChI Key

NLUOEKTUAILDRM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14830891

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

368.46

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.249

Distribution Coefficient, logD

0.758

Water Solubility, LogSw

-3.29

Polar Surface Area

56.124

Acid Dissociation Constant (pKa)

5.41

Base Dissociation Constant (pKb)

5.26

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

31.60

D475-0073 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

SmartTM Library (51161 compounds)

Epigenetics Focused Set (26518 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Nervous system
  • Cardiovascular
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with D475-0073 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D475-0073?
Check Price and Availability of D475-0073, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D475-0073 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D475-0073
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D475-0073
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D475-0073 available by request