D475-0151 Screening compound: N-(2-fluorophenyl)-2-{5-hydroxy-3-methyl-1-[4-(4-methylphenyl)-1,3-thiazol-2-yl]-1H-pyrazol-4-yl}acetamide

D475-0151 Screening compound: N-(2-fluorophenyl)-2-{5-hydroxy-3-methyl-1-[4-(4-methylphenyl)-1,3-thiazol-2-yl]-1H-pyrazol-4-yl}acetamide
D475-0151 Screening compound: N-(2-fluorophenyl)-2-{5-hydroxy-3-methyl-1-[4-(4-methylphenyl)-1,3-thiazol-2-yl]-1H-pyrazol-4-yl}acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D475-0151
N-(2-fluorophenyl)-2-{5-hydroxy-3-methyl-1-[4-(4-methylphenyl)-1,3-thiazol-2-yl]-1H-pyrazol-4-yl}acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D475-0151

Molecular Formula

C22H19FN4O2S (C22 H19 FN4 O2 S)

Compound Name

N-(2-fluorophenyl)-2-{5-hydroxy-3-methyl-1-[4-(4-methylphenyl)-1,3-thiazol-2-yl]-1H-pyrazol-4-yl}acetamide

IUPAC name

N-(2-fluorophenyl)-2-{5-hydroxy-3-methyl-1-[4-(4-methylphenyl)-13-thiazol-2-yl]-1H-pyrazol-4-yl}acetamide

SMILES

Cc(c(CC(Nc(cccc1)c1F)=O)c1O)nn1-c1nc(-c2ccc(C)cc2)cs1

InChI

InChI=1S/C22H19FN4O2S/c1-13-7-9-15(10-8-13)19-12-30-22(25-19)27-21(29)16(14(2)26-27)11-20(28)24-18-6-4-3-5-17(18)23/h3-10,12,29H,11H2,1-2H3,(H,24,28)

InChI Key

XBVIWLCMZUPWEG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27588375

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

422.48

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.451

Distribution Coefficient, logD

1.960

Water Solubility, LogSw

-4.32

Polar Surface Area

61.817

Acid Dissociation Constant (pKa)

5.41

Base Dissociation Constant (pKb)

6.01

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

13.60

D475-0151 in Drug Discovery

Included in Screening Libraries

Protein Kinases Inhibitors Library (36801 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with D475-0151 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D475-0151?
Check Price and Availability of D475-0151, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D475-0151 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D475-0151
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D475-0151
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D475-0151 available by request