D475-1379 Screening compound: 2-[2-(2-chlorophenyl)-5-methyl-7-oxo-4H,7H-[1,2,4]triazolo[1,5-a]pyrimidin-4-yl]-N-(2,6-dimethylphenyl)acetamide

D475-1379 Screening compound: 2-[2-(2-chlorophenyl)-5-methyl-7-oxo-4H,7H-[1,2,4]triazolo[1,5-a]pyrimidin-4-yl]-N-(2,6-dimethylphenyl)acetamide
D475-1379 Screening compound: 2-[2-(2-chlorophenyl)-5-methyl-7-oxo-4H,7H-[1,2,4]triazolo[1,5-a]pyrimidin-4-yl]-N-(2,6-dimethylphenyl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D475-1379
2-[2-(2-chlorophenyl)-5-methyl-7-oxo-4H,7H-[1,2,4]triazolo[1,5-a]pyrimidin-4-yl]-N-(2,6-dimethylphenyl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D475-1379

Molecular Formula

C22H20ClN5O2 (C22 H20 ClN5 O2)

Compound Name

2-[2-(2-chlorophenyl)-5-methyl-7-oxo-4H,7H-[1,2,4]triazolo[1,5-a]pyrimidin-4-yl]-N-(2,6-dimethylphenyl)acetamide

IUPAC name

2-[2-(2-chlorophenyl)-5-methyl-7-oxo-4H7H-[124]triazolo[15-a]pyrimidin-4-yl]-N-(26-dimethylphenyl)acetamide

SMILES

Cc1cccc(C)c1NC(CN(c1nc(-c(cccc2)c2Cl)nn11)C(C)=CC1=O)=O

InChI

InChI=1S/C22H20ClN5O2/c1-13-7-6-8-14(2)20(13)24-18(29)12-27-15(3)11-19(30)28-22(27)25-21(26-28)16-9-4-5-10-17(16)23/h4-11H,12H2,1-3H3,(H,24,29)

InChI Key

FTINKXCMQFNGLD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27588512

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

421.89

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.776

Distribution Coefficient, logD

3.776

Water Solubility, LogSw

-4.12

Polar Surface Area

60.099

Acid Dissociation Constant (pKa)

12.10

Base Dissociation Constant (pKb)

-1.77

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

18.20

D475-1379 in Drug Discovery

Included in Screening Libraries

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with D475-1379 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D475-1379?
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What is the minimum amount of D475-1379 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D475-1379
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D475-1379
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D475-1379 available by request