D475-2483 Screening compound: N-benzyl-3-{5-hydroxy-3-methyl-1-[4-(4-methylphenyl)-1,3-thiazol-2-yl]-1H-pyrazol-4-yl}-N-methylpropanamide

D475-2483 Screening compound: N-benzyl-3-{5-hydroxy-3-methyl-1-[4-(4-methylphenyl)-1,3-thiazol-2-yl]-1H-pyrazol-4-yl}-N-methylpropanamide
D475-2483 Screening compound: N-benzyl-3-{5-hydroxy-3-methyl-1-[4-(4-methylphenyl)-1,3-thiazol-2-yl]-1H-pyrazol-4-yl}-N-methylpropanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D475-2483
N-benzyl-3-{5-hydroxy-3-methyl-1-[4-(4-methylphenyl)-1,3-thiazol-2-yl]-1H-pyrazol-4-yl}-N-methylpropanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D475-2483

Molecular Formula

C25H26N4O2S (C25 H26 N4 O2 S)

Compound Name

N-benzyl-3-{5-hydroxy-3-methyl-1-[4-(4-methylphenyl)-1,3-thiazol-2-yl]-1H-pyrazol-4-yl}-N-methylpropanamide

IUPAC name

N-benzyl-3-{5-hydroxy-3-methyl-1-[4-(4-methylphenyl)-13-thiazol-2-yl]-1H-pyrazol-4-yl}-N-methylpropanamide

SMILES

Cc(c(CCC(N(C)Cc1ccccc1)=O)c1O)nn1-c1nc(-c2ccc(C)cc2)cs1

InChI

InChI=1S/C25H26N4O2S/c1-17-9-11-20(12-10-17)22-16-32-25(26-22)29-24(31)21(18(2)27-29)13-14-23(30)28(3)15-19-7-5-4-6-8-19/h4-12,16,31H,13-15H2,1-3H3

InChI Key

LTGDHFVQAUFPDU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27588639

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

446.57

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.157

Distribution Coefficient, logD

3.171

Water Solubility, LogSw

-4.93

Polar Surface Area

55.260

Acid Dissociation Constant (pKa)

5.92

Base Dissociation Constant (pKb)

6.14

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

24.00

D475-2483 in Drug Discovery

Included in Screening Libraries

Protein Kinases Inhibitors Library (36801 compounds)

SmartTM Library (51161 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with D475-2483 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D475-2483?
Check Price and Availability of D475-2483, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D475-2483 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D475-2483
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D475-2483
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D475-2483 available by request