D475-2800 Screening compound: N-(2,4-dimethoxyphenyl)-3-[1-(4,5-dimethyl-1,3-thiazol-2-yl)-5-hydroxy-3-methyl-1H-pyrazol-4-yl]propanamide

D475-2800 Screening compound: N-(2,4-dimethoxyphenyl)-3-[1-(4,5-dimethyl-1,3-thiazol-2-yl)-5-hydroxy-3-methyl-1H-pyrazol-4-yl]propanamide
D475-2800 Screening compound: N-(2,4-dimethoxyphenyl)-3-[1-(4,5-dimethyl-1,3-thiazol-2-yl)-5-hydroxy-3-methyl-1H-pyrazol-4-yl]propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D475-2800
N-(2,4-dimethoxyphenyl)-3-[1-(4,5-dimethyl-1,3-thiazol-2-yl)-5-hydroxy-3-methyl-1H-pyrazol-4-yl]propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D475-2800

Molecular Formula

C20H24N4O4S (C20 H24 N4 O4 S)

Compound Name

N-(2,4-dimethoxyphenyl)-3-[1-(4,5-dimethyl-1,3-thiazol-2-yl)-5-hydroxy-3-methyl-1H-pyrazol-4-yl]propanamide

IUPAC name

N-(24-dimethoxyphenyl)-3-[1-(45-dimethyl-13-thiazol-2-yl)-5-hydroxy-3-methyl-1H-pyrazol-4-yl]propanamide

SMILES

Cc1c(C)sc(-n2nc(C)c(CCC(Nc(ccc(OC)c3)c3OC)=O)c2O)n1

InChI

InChI=1S/C20H24N4O4S/c1-11-13(3)29-20(21-11)24-19(26)15(12(2)23-24)7-9-18(25)22-16-8-6-14(27-4)10-17(16)28-5/h6,8,10,26H,7,9H2,1-5H3,(H,22,25)

InChI Key

VLZVDGOCWRRREM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27588678

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

416.5

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.552

Distribution Coefficient, logD

2.552

Water Solubility, LogSw

-2.95

Polar Surface Area

77.840

Acid Dissociation Constant (pKa)

6.53

Base Dissociation Constant (pKb)

8.31

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

35.00

D475-2800 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

RNA-Protein Interaction Inhibitors Library (1986 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with D475-2800 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D475-2800?
Check Price and Availability of D475-2800, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D475-2800 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D475-2800
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D475-2800
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D475-2800 available by request