D481-0123 Screening compound: N-(2-methoxyphenyl)-3-(5-methyl-2-{[(4-methylphenyl)methyl]amino}-7-oxo-4H,7H-[1,2,4]triazolo[1,5-a]pyrimidin-6-yl)propanamide

D481-0123 Screening compound: N-(2-methoxyphenyl)-3-(5-methyl-2-{[(4-methylphenyl)methyl]amino}-7-oxo-4H,7H-[1,2,4]triazolo[1,5-a]pyrimidin-6-yl)propanamide
D481-0123 Screening compound: N-(2-methoxyphenyl)-3-(5-methyl-2-{[(4-methylphenyl)methyl]amino}-7-oxo-4H,7H-[1,2,4]triazolo[1,5-a]pyrimidin-6-yl)propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D481-0123
N-(2-methoxyphenyl)-3-(5-methyl-2-{[(4-methylphenyl)methyl]amino}-7-oxo-4H,7H-[1,2,4]triazolo[1,5-a]pyrimidin-6-yl)propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D481-0123

Molecular Formula

C24H26N6O3 (C24 H26 N6 O3)

Compound Name

N-(2-methoxyphenyl)-3-(5-methyl-2-{[(4-methylphenyl)methyl]amino}-7-oxo-4H,7H-[1,2,4]triazolo[1,5-a]pyrimidin-6-yl)propanamide

IUPAC name

N-(2-methoxyphenyl)-3-(5-methyl-2-{[(4-methylphenyl)methyl]amino}-7-oxo-4H7H-[124]triazolo[15-a]pyrimidin-6-yl)propanamide

SMILES

Cc1ccc(CNc(nc2NC(C)=C3CCC(Nc(cccc4)c4OC)=O)nn2C3=O)cc1

InChI

InChI=1S/C24H26N6O3/c1-15-8-10-17(11-9-15)14-25-23-28-24-26-16(2)18(22(32)30(24)29-23)12-13-21(31)27-19-6-4-5-7-20(19)33-3/h4-11H,12-14H2,1-3H3,(H,27,31)(H2,25,26,28,29)

InChI Key

YOTYVGAOJCUOCI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD13919759

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

446.51

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

2.930

Distribution Coefficient, logD

2.887

Water Solubility, LogSw

-3.37

Polar Surface Area

91.702

Acid Dissociation Constant (pKa)

8.38

Base Dissociation Constant (pKb)

0.32

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.00

D481-0123 in Drug Discovery

Included in Screening Libraries

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with D481-0123 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D481-0123?
Check Price and Availability of D481-0123, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D481-0123 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D481-0123
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D481-0123
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D481-0123 available by request