D481-0408 Screening compound: N-[5,7-bis(4-methylphenyl)-4H,7H-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]benzenesulfonamide

D481-0408 Screening compound: N-[5,7-bis(4-methylphenyl)-4H,7H-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]benzenesulfonamide
D481-0408 Screening compound: N-[5,7-bis(4-methylphenyl)-4H,7H-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]benzenesulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D481-0408
N-[5,7-bis(4-methylphenyl)-4H,7H-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]benzenesulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D481-0408

Molecular Formula

C25H23N5O2S (C25 H23 N5 O2 S)

Compound Name

N-[5,7-bis(4-methylphenyl)-4H,7H-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]benzenesulfonamide

IUPAC name

N-[57-bis(4-methylphenyl)-4H7H-[124]triazolo[15-a]pyrimidin-2-yl]benzenesulfonamide

SMILES

Cc1ccc(C2n3nc(NS(c4ccccc4)(=O)=O)nc3NC(c3ccc(C)cc3)=C2)cc1

InChI

InChI=1S/C25H23N5O2S/c1-17-8-12-19(13-9-17)22-16-23(20-14-10-18(2)11-15-20)30-25(26-22)27-24(28-30)29-33(31,32)21-6-4-3-5-7-21/h3-16,23H,1-2H3,(H2,26,27,28,29)/t23-/m0/s1

InChI Key

CWTAEKRQHYYERM-QHCPKHFHSA-N

MDL Number (MFCD)

MFCD27588777

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

457.56

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.496

Distribution Coefficient, logD

4.254

Water Solubility, LogSw

-5.71

Polar Surface Area

79.443

Acid Dissociation Constant (pKa)

6.18

Base Dissociation Constant (pKb)

-3.13

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

12.00

D481-0408 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

Anticancer Library (62698 compounds)

PI3K-Targeted Library (17255 compounds)

Targeted Diversity Library (40567 compounds)

Type II Kinase Inhibitors Library (6956 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Digestive system
  • Hemic and lymphatic
  • Endocrine
Targets:
  • Kinases
  • Kinases
  • Kinases

References: we are preparing a list of scientific research reports with D481-0408 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D481-0408?
Check Price and Availability of D481-0408, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D481-0408 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D481-0408
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D481-0408
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D481-0408 available by request