D481-0409 Screening compound: N-[5,7-bis(4-methylphenyl)-4H,7H-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]-4-methylbenzene-1-sulfonamide

D481-0409 Screening compound: N-[5,7-bis(4-methylphenyl)-4H,7H-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]-4-methylbenzene-1-sulfonamide
D481-0409 Screening compound: N-[5,7-bis(4-methylphenyl)-4H,7H-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]-4-methylbenzene-1-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D481-0409
N-[5,7-bis(4-methylphenyl)-4H,7H-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]-4-methylbenzene-1-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D481-0409

Molecular Formula

C26H25N5O2S (C26 H25 N5 O2 S)

Compound Name

N-[5,7-bis(4-methylphenyl)-4H,7H-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]-4-methylbenzene-1-sulfonamide

IUPAC name

N-[57-bis(4-methylphenyl)-4H7H-[124]triazolo[15-a]pyrimidin-2-yl]-4-methylbenzene-1-sulfonamide

SMILES

Cc1ccc(C2n3nc(NS(c4ccc(C)cc4)(=O)=O)nc3NC(c3ccc(C)cc3)=C2)cc1

InChI

InChI=1S/C26H25N5O2S/c1-17-4-10-20(11-5-17)23-16-24(21-12-6-18(2)7-13-21)31-26(27-23)28-25(29-31)30-34(32,33)22-14-8-19(3)9-15-22/h4-16,24H,1-3H3,(H2,27,28,29,30)/t24-/m0/s1

InChI Key

IGYFNYOSPXPGIJ-DEOSSOPVSA-N

MDL Number (MFCD)

MFCD27588778

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

471.58

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

6.105

Distribution Coefficient, logD

4.862

Water Solubility, LogSw

-5.74

Polar Surface Area

79.443

Acid Dissociation Constant (pKa)

6.18

Base Dissociation Constant (pKb)

-3.13

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

15.40

D481-0409 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

KRAS-Targeted Library (16000 compounds)

PI3K-Targeted Library (17255 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases
  • Kinases

References: we are preparing a list of scientific research reports with D481-0409 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D481-0409?
Check Price and Availability of D481-0409, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D481-0409 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D481-0409
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D481-0409
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D481-0409 available by request