D481-0653 Screening compound: N-[7-(2-chlorophenyl)-5-(4-chlorophenyl)-4H,7H-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]-2-methylpropanamide

D481-0653 Screening compound: N-[7-(2-chlorophenyl)-5-(4-chlorophenyl)-4H,7H-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]-2-methylpropanamide
D481-0653 Screening compound: N-[7-(2-chlorophenyl)-5-(4-chlorophenyl)-4H,7H-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]-2-methylpropanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D481-0653
N-[7-(2-chlorophenyl)-5-(4-chlorophenyl)-4H,7H-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]-2-methylpropanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D481-0653

Molecular Formula

C21H19Cl2N5O (C21 H19 Cl2 N5 O)

Compound Name

N-[7-(2-chlorophenyl)-5-(4-chlorophenyl)-4H,7H-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]-2-methylpropanamide

IUPAC name

N-[7-(2-chlorophenyl)-5-(4-chlorophenyl)-4H7H-[124]triazolo[15-a]pyrimidin-2-yl]-2-methylpropanamide

SMILES

CC(C)C(Nc1nn(C(C=C(c(cc2)ccc2Cl)N2)c(cccc3)c3Cl)c2n1)=O

InChI

InChI=1S/C21H19Cl2N5O/c1-12(2)19(29)25-20-26-21-24-17(13-7-9-14(22)10-8-13)11-18(28(21)27-20)15-5-3-4-6-16(15)23/h3-12,18H,1-2H3,(H2,24,25,26,27,29)/t18-/m0/s1

InChI Key

JKQQHQXLELEMDA-SFHVURJKSA-N

MDL Number (MFCD)

MFCD27588832

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

428.32

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.618

Distribution Coefficient, logD

5.617

Water Solubility, LogSw

-5.97

Polar Surface Area

62.156

Acid Dissociation Constant (pKa)

9.84

Base Dissociation Constant (pKb)

-2.03

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

19.00

D481-0653 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with D481-0653 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D481-0653?
Check Price and Availability of D481-0653, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D481-0653 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D481-0653
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D481-0653
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D481-0653 available by request