D481-0741 Screening compound: N-[7-(2-chloro-6-fluorophenyl)-5-phenyl-4H,7H-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]furan-2-carboxamide

D481-0741 Screening compound: N-[7-(2-chloro-6-fluorophenyl)-5-phenyl-4H,7H-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]furan-2-carboxamide
D481-0741 Screening compound: N-[7-(2-chloro-6-fluorophenyl)-5-phenyl-4H,7H-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]furan-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D481-0741
N-[7-(2-chloro-6-fluorophenyl)-5-phenyl-4H,7H-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]furan-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D481-0741

Molecular Formula

C22H15ClFN5O2 (C22 H15 ClFN5 O2)

Compound Name

N-[7-(2-chloro-6-fluorophenyl)-5-phenyl-4H,7H-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]furan-2-carboxamide

IUPAC name

N-[7-(2-chloro-6-fluorophenyl)-5-phenyl-4H7H-[124]triazolo[15-a]pyrimidin-2-yl]furan-2-carboxamide

SMILES

O=C(c1ccco1)Nc1nn(C(C=C(c2ccccc2)N2)c(c(F)ccc3)c3Cl)c2n1

InChI

InChI=1S/C22H15ClFN5O2/c23-14-8-4-9-15(24)19(14)17-12-16(13-6-2-1-3-7-13)25-22-27-21(28-29(17)22)26-20(30)18-10-5-11-31-18/h1-12,17H,(H2,25,26,27,28,30)/t17-/m0/s1

InChI Key

KEWSDESKCWJGFH-KRWDZBQOSA-N

MDL Number (MFCD)

MFCD27588872

Chemical and Physical Properties

Saltdata

HCl

Molecular Weight

435.84

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.555

Distribution Coefficient, logD

4.545

Water Solubility, LogSw

-4.70

Polar Surface Area

70.463

Acid Dissociation Constant (pKa)

9.03

Base Dissociation Constant (pKb)

-3.30

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

4.50

D481-0741 in Drug Discovery

Included in Screening Libraries

Anti-infective Library (19449 compounds)

Anticancer Library (62698 compounds)

Antiviral HBV Library (10007 compounds)

Antiviral Library (67538 compounds)

Protein-Protein Interaction Library (218420 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Epitranscriptome Focused Small Molecule Library (20952 compounds)

Type II Kinase Inhibitors Library (6956 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
  • Cancer
  • Antiviral
  • Infections
  • Immune system
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
  • Digestive system
  • Hemic and lymphatic
  • Endocrine
Mechanism of action:
  • PPI modulators
  • Receptor's ligands
  • Epigenetic
Targets:
  • GPCR
  • Kinases

References: we are preparing a list of scientific research reports with D481-0741 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D481-0741?
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What is the minimum amount of D481-0741 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D481-0741
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D481-0741
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D481-0741 available by request