D481-1719 Screening compound: 2-[2-(4-chloro-3,5-dimethyl-1H-pyrazol-1-yl)-1,3-thiazol-4-yl]-N-[(2-fluorophenyl)methyl]acetamide

D481-1719 Screening compound: 2-[2-(4-chloro-3,5-dimethyl-1H-pyrazol-1-yl)-1,3-thiazol-4-yl]-N-[(2-fluorophenyl)methyl]acetamide
D481-1719 Screening compound: 2-[2-(4-chloro-3,5-dimethyl-1H-pyrazol-1-yl)-1,3-thiazol-4-yl]-N-[(2-fluorophenyl)methyl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D481-1719
2-[2-(4-chloro-3,5-dimethyl-1H-pyrazol-1-yl)-1,3-thiazol-4-yl]-N-[(2-fluorophenyl)methyl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D481-1719

Molecular Formula

C17H16ClFN4OS (C17 H16 ClFN4 OS)

Compound Name

2-[2-(4-chloro-3,5-dimethyl-1H-pyrazol-1-yl)-1,3-thiazol-4-yl]-N-[(2-fluorophenyl)methyl]acetamide

IUPAC name

2-[2-(4-chloro-35-dimethyl-1H-pyrazol-1-yl)-13-thiazol-4-yl]-N-[(2-fluorophenyl)methyl]acetamide

SMILES

Cc(n(-c1nc(CC(NCc(cccc2)c2F)=O)cs1)nc1C)c1Cl

InChI

InChI=1S/C17H16ClFN4OS/c1-10-16(18)11(2)23(22-10)17-21-13(9-25-17)7-15(24)20-8-12-5-3-4-6-14(12)19/h3-6,9H,7-8H2,1-2H3,(H,20,24)

InChI Key

KVZCVQCROSFHHX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27588944

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

378.86

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.719

Distribution Coefficient, logD

3.719

Water Solubility, LogSw

-4.37

Polar Surface Area

49.172

Acid Dissociation Constant (pKa)

13.02

Base Dissociation Constant (pKb)

2.96

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

23.50

D481-1719 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with D481-1719 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D481-1719?
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What is the minimum amount of D481-1719 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D481-1719
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D481-1719
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D481-1719 available by request