D481-2355 Screening compound: N-[4-(4-chlorophenyl)-6-phenylpyrimidin-2-yl]-2-(4-phenylpiperazin-1-yl)acetamide

D481-2355 Screening compound: N-[4-(4-chlorophenyl)-6-phenylpyrimidin-2-yl]-2-(4-phenylpiperazin-1-yl)acetamide
D481-2355 Screening compound: N-[4-(4-chlorophenyl)-6-phenylpyrimidin-2-yl]-2-(4-phenylpiperazin-1-yl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D481-2355
N-[4-(4-chlorophenyl)-6-phenylpyrimidin-2-yl]-2-(4-phenylpiperazin-1-yl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D481-2355

Molecular Formula

C28H26ClN5O (C28 H26 ClN5 O)

Compound Name

N-[4-(4-chlorophenyl)-6-phenylpyrimidin-2-yl]-2-(4-phenylpiperazin-1-yl)acetamide

IUPAC name

N-[4-(4-chlorophenyl)-6-phenylpyrimidin-2-yl]-2-(4-phenylpiperazin-1-yl)acetamide

SMILES

O=C(CN(CC1)CCN1c1ccccc1)Nc1nc(-c2ccccc2)cc(-c(cc2)ccc2Cl)n1

InChI

InChI=1S/C28H26ClN5O/c29-23-13-11-22(12-14-23)26-19-25(21-7-3-1-4-8-21)30-28(31-26)32-27(35)20-33-15-17-34(18-16-33)24-9-5-2-6-10-24/h1-14,19H,15-18,20H2,(H,30,31,32,35)

InChI Key

IOYZAXSLUBVWHS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14831788

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

484

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

6.801

Distribution Coefficient, logD

6.800

Water Solubility, LogSw

-6.55

Polar Surface Area

49.543

Acid Dissociation Constant (pKa)

11.82

Base Dissociation Constant (pKb)

4.93

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

17.90

D481-2355 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS Targets (44014 compounds)

Neurotransmitter Transporter Inhibitors Library (11024 compounds)

Proline Kinase Library (2105 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Nervous system
  • Cancer
  • Digestive system
  • Nervous system
  • Male
  • Female
  • Endocrine
Targets:
  • GPCR
  • Ion Channels
  • Kinases

References: we are preparing a list of scientific research reports with D481-2355 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D481-2355?
Check Price and Availability of D481-2355, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D481-2355 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D481-2355
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D481-2355
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D481-2355 available by request