D481-2364 Screening compound: N-[4-(4-chlorophenyl)-6-phenylpyrimidin-2-yl]-2-[(4-fluorophenyl)amino]acetamide

D481-2364 Screening compound: N-[4-(4-chlorophenyl)-6-phenylpyrimidin-2-yl]-2-[(4-fluorophenyl)amino]acetamide
D481-2364 Screening compound: N-[4-(4-chlorophenyl)-6-phenylpyrimidin-2-yl]-2-[(4-fluorophenyl)amino]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D481-2364
N-[4-(4-chlorophenyl)-6-phenylpyrimidin-2-yl]-2-[(4-fluorophenyl)amino]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D481-2364

Molecular Formula

C24H18ClFN4O (C24 H18 ClFN4 O)

Compound Name

N-[4-(4-chlorophenyl)-6-phenylpyrimidin-2-yl]-2-[(4-fluorophenyl)amino]acetamide

IUPAC name

N-[4-(4-chlorophenyl)-6-phenylpyrimidin-2-yl]-2-[(4-fluorophenyl)amino]acetamide

SMILES

O=C(CNc(cc1)ccc1F)Nc1nc(-c2ccccc2)cc(-c(cc2)ccc2Cl)n1

InChI

InChI=1S/C24H18ClFN4O/c25-18-8-6-17(7-9-18)22-14-21(16-4-2-1-3-5-16)28-24(29-22)30-23(31)15-27-20-12-10-19(26)11-13-20/h1-14,27H,15H2,(H,28,29,30,31)

InChI Key

FBBYNWZUFQIMAW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14831792

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

432.88

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

6.745

Distribution Coefficient, logD

6.745

Water Solubility, LogSw

-6.56

Polar Surface Area

52.785

Acid Dissociation Constant (pKa)

11.97

Base Dissociation Constant (pKb)

4.87

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

4.20

D481-2364 in Drug Discovery

Included in Screening Libraries

Chelators targeting matrix metalloproteinases library (8930 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Cardiovascular
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with D481-2364 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D481-2364?
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What is the minimum amount of D481-2364 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D481-2364
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D481-2364
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D481-2364 available by request