D481-2421 Screening compound: N-[4-(4-chlorophenyl)-6-(4-methoxyphenyl)pyrimidin-2-yl]-2-[(3-methoxyphenyl)amino]acetamide

D481-2421 Screening compound: N-[4-(4-chlorophenyl)-6-(4-methoxyphenyl)pyrimidin-2-yl]-2-[(3-methoxyphenyl)amino]acetamide
D481-2421 Screening compound: N-[4-(4-chlorophenyl)-6-(4-methoxyphenyl)pyrimidin-2-yl]-2-[(3-methoxyphenyl)amino]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D481-2421
N-[4-(4-chlorophenyl)-6-(4-methoxyphenyl)pyrimidin-2-yl]-2-[(3-methoxyphenyl)amino]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D481-2421

Molecular Formula

C26H23ClN4O3 (C26 H23 ClN4 O3)

Compound Name

N-[4-(4-chlorophenyl)-6-(4-methoxyphenyl)pyrimidin-2-yl]-2-[(3-methoxyphenyl)amino]acetamide

IUPAC name

N-[4-(4-chlorophenyl)-6-(4-methoxyphenyl)pyrimidin-2-yl]-2-[(3-methoxyphenyl)amino]acetamide

SMILES

COc(cc1)ccc1-c1cc(-c(cc2)ccc2Cl)nc(NC(CNc2cc(OC)ccc2)=O)n1

InChI

InChI=1S/C26H23ClN4O3/c1-33-21-12-8-18(9-13-21)24-15-23(17-6-10-19(27)11-7-17)29-26(30-24)31-25(32)16-28-20-4-3-5-22(14-20)34-2/h3-15,28H,16H2,1-2H3,(H,29,30,31,32)

InChI Key

IWXNVDNPLZZGMV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27589074

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

474.95

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

6.743

Distribution Coefficient, logD

6.743

Water Solubility, LogSw

-6.48

Polar Surface Area

67.872

Acid Dissociation Constant (pKa)

11.97

Base Dissociation Constant (pKb)

2.32

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

11.50

D481-2421 in Drug Discovery

Included in Screening Libraries

Chelators targeting matrix metalloproteinases library (8930 compounds)

Regenerative Medicine Focused Library (23016 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Cardiovascular
  • Musculoskeletal
  • Digestive system
  • Hemic and lymphatic
  • Cardiovascular
  • Skin
  • wounds
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with D481-2421 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D481-2421?
Check Price and Availability of D481-2421, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D481-2421 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D481-2421
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D481-2421
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D481-2421 available by request