D481-2467 Screening compound: N-[4,6-bis(4-chlorophenyl)pyrimidin-2-yl]-2-[(4-ethoxyphenyl)amino]acetamide

D481-2467 Screening compound: N-[4,6-bis(4-chlorophenyl)pyrimidin-2-yl]-2-[(4-ethoxyphenyl)amino]acetamide
D481-2467 Screening compound: N-[4,6-bis(4-chlorophenyl)pyrimidin-2-yl]-2-[(4-ethoxyphenyl)amino]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D481-2467
N-[4,6-bis(4-chlorophenyl)pyrimidin-2-yl]-2-[(4-ethoxyphenyl)amino]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D481-2467

Molecular Formula

C26H22Cl2N4O2 (C26 H22 Cl2 N4 O2)

Compound Name

N-[4,6-bis(4-chlorophenyl)pyrimidin-2-yl]-2-[(4-ethoxyphenyl)amino]acetamide

IUPAC name

N-[46-bis(4-chlorophenyl)pyrimidin-2-yl]-2-[(4-ethoxyphenyl)amino]acetamide

SMILES

CCOc(cc1)ccc1NCC(Nc1nc(-c(cc2)ccc2Cl)cc(-c(cc2)ccc2Cl)n1)=O

InChI

InChI=1S/C26H22Cl2N4O2/c1-2-34-22-13-11-21(12-14-22)29-16-25(33)32-26-30-23(17-3-7-19(27)8-4-17)15-24(31-26)18-5-9-20(28)10-6-18/h3-15,29H,2,16H2,1H3,(H,30,31,32,33)

InChI Key

QFVLTNWFKBRWTN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14831824

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

493.39

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

7.785

Distribution Coefficient, logD

7.785

Water Solubility, LogSw

-6.52

Polar Surface Area

59.908

Acid Dissociation Constant (pKa)

11.97

Base Dissociation Constant (pKb)

3.09

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

11.50

D481-2467 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Chelators targeting matrix metalloproteinases library (8930 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Cardiovascular
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with D481-2467 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D481-2467?
Check Price and Availability of D481-2467, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D481-2467 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D481-2467
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D481-2467
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D481-2467 available by request