D481-2579 Screening compound: N-[4-(4-chlorophenyl)-6-(4-methylphenyl)pyrimidin-2-yl]-2-[(4-fluorophenyl)amino]acetamide

D481-2579 Screening compound: N-[4-(4-chlorophenyl)-6-(4-methylphenyl)pyrimidin-2-yl]-2-[(4-fluorophenyl)amino]acetamide
D481-2579 Screening compound: N-[4-(4-chlorophenyl)-6-(4-methylphenyl)pyrimidin-2-yl]-2-[(4-fluorophenyl)amino]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D481-2579
N-[4-(4-chlorophenyl)-6-(4-methylphenyl)pyrimidin-2-yl]-2-[(4-fluorophenyl)amino]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D481-2579

Molecular Formula

C25H20ClFN4O (C25 H20 ClFN4 O)

Compound Name

N-[4-(4-chlorophenyl)-6-(4-methylphenyl)pyrimidin-2-yl]-2-[(4-fluorophenyl)amino]acetamide

IUPAC name

N-[4-(4-chlorophenyl)-6-(4-methylphenyl)pyrimidin-2-yl]-2-[(4-fluorophenyl)amino]acetamide

SMILES

Cc(cc1)ccc1-c1cc(-c(cc2)ccc2Cl)nc(NC(CNc(cc2)ccc2F)=O)n1

InChI

InChI=1S/C25H20ClFN4O/c1-16-2-4-17(5-3-16)22-14-23(18-6-8-19(26)9-7-18)30-25(29-22)31-24(32)15-28-21-12-10-20(27)11-13-21/h2-14,28H,15H2,1H3,(H,29,30,31,32)

InChI Key

IKFQYNBBSDYLNF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14831867

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

446.91

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

7.274

Distribution Coefficient, logD

7.274

Water Solubility, LogSw

-6.45

Polar Surface Area

52.785

Acid Dissociation Constant (pKa)

11.97

Base Dissociation Constant (pKb)

4.87

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

8.00

D481-2579 in Drug Discovery

Included in Screening Libraries

Chelators targeting matrix metalloproteinases library (8930 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Cardiovascular
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with D481-2579 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D481-2579?
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What is the minimum amount of D481-2579 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D481-2579
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D481-2579
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D481-2579 available by request