D482-2705 Screening compound: 1-(2-{[(4-chlorophenyl)methyl]sulfanyl}-6-(4-methylphenyl)pyrimidin-4-yl)piperidine-4-carboxamide

D482-2705 Screening compound: 1-(2-{[(4-chlorophenyl)methyl]sulfanyl}-6-(4-methylphenyl)pyrimidin-4-yl)piperidine-4-carboxamide
D482-2705 Screening compound: 1-(2-{[(4-chlorophenyl)methyl]sulfanyl}-6-(4-methylphenyl)pyrimidin-4-yl)piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D482-2705
1-(2-{[(4-chlorophenyl)methyl]sulfanyl}-6-(4-methylphenyl)pyrimidin-4-yl)piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D482-2705

Molecular Formula

C24H25ClN4OS (C24 H25 ClN4 OS)

Compound Name

1-(2-{[(4-chlorophenyl)methyl]sulfanyl}-6-(4-methylphenyl)pyrimidin-4-yl)piperidine-4-carboxamide

IUPAC name

1-(2-{[(4-chlorophenyl)methyl]sulfanyl}-6-(4-methylphenyl)pyrimidin-4-yl)piperidine-4-carboxamide

SMILES

Cc(cc1)ccc1-c1nc(SCc(cc2)ccc2Cl)nc(N(CC2)CCC2C(N)=O)c1

InChI

InChI=1S/C24H25ClN4OS/c1-16-2-6-18(7-3-16)21-14-22(29-12-10-19(11-13-29)23(26)30)28-24(27-21)31-15-17-4-8-20(25)9-5-17/h2-9,14,19H,10-13,15H2,1H3,(H2,26,30)

InChI Key

UGVGQYULZZCDCB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD10090550

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

453.01

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.786

Distribution Coefficient, logD

5.784

Water Solubility, LogSw

-6.02

Polar Surface Area

53.963

Acid Dissociation Constant (pKa)

14.92

Base Dissociation Constant (pKb)

4.95

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

29.20

D482-2705 in Drug Discovery

Included in Screening Libraries

Autophagy-Targeted Library (4564 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system

References: we are preparing a list of scientific research reports with D482-2705 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D482-2705?
Check Price and Availability of D482-2705, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D482-2705 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D482-2705
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D482-2705
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D482-2705 available by request