D483-1463 Screening compound: N-(3-chloro-4-methoxyphenyl)-2-{[5-({2,8-dimethyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl}methyl)-4-methyl-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide

D483-1463 Screening compound: N-(3-chloro-4-methoxyphenyl)-2-{[5-({2,8-dimethyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl}methyl)-4-methyl-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide
D483-1463 Screening compound: N-(3-chloro-4-methoxyphenyl)-2-{[5-({2,8-dimethyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl}methyl)-4-methyl-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D483-1463
N-(3-chloro-4-methoxyphenyl)-2-{[5-({2,8-dimethyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl}methyl)-4-methyl-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D483-1463

Molecular Formula

C23H23ClN6O3S (C23 H23 ClN6 O3 S)

Compound Name

N-(3-chloro-4-methoxyphenyl)-2-{[5-({2,8-dimethyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl}methyl)-4-methyl-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide

IUPAC name

N-(3-chloro-4-methoxyphenyl)-2-{[5-({28-dimethyl-4-oxo-4H-pyrido[12-a]pyrimidin-3-yl}methyl)-4-methyl-4H-124-triazol-3-yl]sulfanyl}acetamide

SMILES

CC(C=CN12)=CC2=NC(C)=C(Cc(n2C)nnc2SCC(Nc(cc2)cc(Cl)c2OC)=O)C1=O

InChI

InChI=1S/C23H23ClN6O3S/c1-13-7-8-30-19(9-13)25-14(2)16(22(30)32)11-20-27-28-23(29(20)3)34-12-21(31)26-15-5-6-18(33-4)17(24)10-15/h5-10H,11-12H2,1-4H3,(H,26,31)

InChI Key

YSKWEFLCZSZLRT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14831980

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

498.99

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

2.370

Distribution Coefficient, logD

2.370

Water Solubility, LogSw

-3.31

Polar Surface Area

81.704

Acid Dissociation Constant (pKa)

10.59

Base Dissociation Constant (pKb)

3.18

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

26.10

D483-1463 in Drug Discovery

Included in Screening Libraries

Histone Deacetylases (HDAC) Targeted Library (9760 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Endocrine
  • Immune system
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with D483-1463 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D483-1463?
Check Price and Availability of D483-1463, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D483-1463 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D483-1463
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D483-1463
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D483-1463 available by request