D483-1566 Screening compound: 2-{[5-({2,9-dimethyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl}methyl)-4-methyl-4H-1,2,4-triazol-3-yl]sulfanyl}-N-(5-ethyl-1,3,4-thiadiazol-2-yl)acetamide

D483-1566 Screening compound: 2-{[5-({2,9-dimethyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl}methyl)-4-methyl-4H-1,2,4-triazol-3-yl]sulfanyl}-N-(5-ethyl-1,3,4-thiadiazol-2-yl)acetamide
D483-1566 Screening compound: 2-{[5-({2,9-dimethyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl}methyl)-4-methyl-4H-1,2,4-triazol-3-yl]sulfanyl}-N-(5-ethyl-1,3,4-thiadiazol-2-yl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D483-1566
2-{[5-({2,9-dimethyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl}methyl)-4-methyl-4H-1,2,4-triazol-3-yl]sulfanyl}-N-(5-ethyl-1,3,4-thiadiazol-2-yl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D483-1566

Molecular Formula

C20H22N8O2S2 (C20 H22 N8 O2 S2)

Compound Name

2-{[5-({2,9-dimethyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl}methyl)-4-methyl-4H-1,2,4-triazol-3-yl]sulfanyl}-N-(5-ethyl-1,3,4-thiadiazol-2-yl)acetamide

IUPAC name

2-{[5-({29-dimethyl-4-oxo-4H-pyrido[12-a]pyrimidin-3-yl}methyl)-4-methyl-4H-124-triazol-3-yl]sulfanyl}-N-(5-ethyl-134-thiadiazol-2-yl)acetamide

SMILES

CCc1nnc(NC(CSc2nnc(CC3=C(C)N=C(C(C)=CC=C4)N4C3=O)n2C)=O)s1

InChI

InChI=1S/C20H22N8O2S2/c1-5-16-24-25-19(32-16)22-15(29)10-31-20-26-23-14(27(20)4)9-13-12(3)21-17-11(2)7-6-8-28(17)18(13)30/h6-8H,5,9-10H2,1-4H3,(H,22,25,29)

InChI Key

CSULTPPAGYWGPF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27589117

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

470.58

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

1.429

Distribution Coefficient, logD

1.382

Water Solubility, LogSw

-2.01

Polar Surface Area

97.135

Acid Dissociation Constant (pKa)

8.34

Base Dissociation Constant (pKb)

2.83

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

35.00

D483-1566 in Drug Discovery

Included in Screening Libraries

Protein Kinases Inhibitors Library (36801 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with D483-1566 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D483-1566?
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What is the minimum amount of D483-1566 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D483-1566
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D483-1566
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D483-1566 available by request