D483-1829 Screening compound: 8-methyl-2-({[4-methyl-5-({2-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl}methyl)-4H-1,2,4-triazol-3-yl]sulfanyl}methyl)-1,4-dihydroquinolin-4-one

D483-1829 Screening compound: 8-methyl-2-({[4-methyl-5-({2-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl}methyl)-4H-1,2,4-triazol-3-yl]sulfanyl}methyl)-1,4-dihydroquinolin-4-one
D483-1829 Screening compound: 8-methyl-2-({[4-methyl-5-({2-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl}methyl)-4H-1,2,4-triazol-3-yl]sulfanyl}methyl)-1,4-dihydroquinolin-4-one alternative view

Chemical Structure Depiction of ChemDiv screening compound D483-1829
8-methyl-2-({[4-methyl-5-({2-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl}methyl)-4H-1,2,4-triazol-3-yl]sulfanyl}methyl)-1,4-dihydroquinolin-4-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D483-1829

Molecular Formula

C24H22N6O2S (C24 H22 N6 O2 S)

Compound Name

8-methyl-2-({[4-methyl-5-({2-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl}methyl)-4H-1,2,4-triazol-3-yl]sulfanyl}methyl)-1,4-dihydroquinolin-4-one

IUPAC name

8-methyl-2-({[4-methyl-5-({2-methyl-4-oxo-4H-pyrido[12-a]pyrimidin-3-yl}methyl)-4H-124-triazol-3-yl]sulfanyl}methyl)-14-dihydroquinolin-4-one

SMILES

Cc1cccc2c1NC(CSc1nnc(CC3=C(C)N=C(C=CC=C4)N4C3=O)n1C)=CC2=O

InChI

InChI=1S/C24H22N6O2S/c1-14-7-6-8-17-19(31)11-16(26-22(14)17)13-33-24-28-27-21(29(24)3)12-18-15(2)25-20-9-4-5-10-30(20)23(18)32/h4-11H,12-13H2,1-3H3,(H,26,31)

InChI Key

ZKNVWCKDGMFLHL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14832050

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

458.54

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.055

Distribution Coefficient, logD

2.047

Water Solubility, LogSw

-2.78

Polar Surface Area

73.467

Acid Dissociation Constant (pKa)

9.13

Base Dissociation Constant (pKb)

2.77

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.80

D483-1829 in Drug Discovery

Included in Screening Libraries

Anti-Inflammatory Library (24602 compounds)

SmartTM Library (51161 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system

References: we are preparing a list of scientific research reports with D483-1829 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D483-1829?
Check Price and Availability of D483-1829, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D483-1829 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D483-1829
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D483-1829
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D483-1829 available by request