D486-0521 Screening compound: 5-(4-chlorophenyl)-N-[2-(dimethylamino)-2-(4-methoxyphenyl)ethyl]-1,2-oxazole-3-carboxamide

D486-0521 Screening compound: 5-(4-chlorophenyl)-N-[2-(dimethylamino)-2-(4-methoxyphenyl)ethyl]-1,2-oxazole-3-carboxamide
D486-0521 Screening compound: 5-(4-chlorophenyl)-N-[2-(dimethylamino)-2-(4-methoxyphenyl)ethyl]-1,2-oxazole-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D486-0521
5-(4-chlorophenyl)-N-[2-(dimethylamino)-2-(4-methoxyphenyl)ethyl]-1,2-oxazole-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D486-0521

Molecular Formula

C21H22ClN3O3 (C21 H22 ClN3 O3)

Compound Name

5-(4-chlorophenyl)-N-[2-(dimethylamino)-2-(4-methoxyphenyl)ethyl]-1,2-oxazole-3-carboxamide

IUPAC name

5-(4-chlorophenyl)-N-[2-(dimethylamino)-2-(4-methoxyphenyl)ethyl]-12-oxazole-3-carboxamide

SMILES

CN(C)C(CNC(c1noc(-c(cc2)ccc2Cl)c1)=O)c(cc1)ccc1OC

InChI

InChI=1S/C21H22ClN3O3/c1-25(2)19(14-6-10-17(27-3)11-7-14)13-23-21(26)18-12-20(28-24-18)15-4-8-16(22)9-5-15/h4-12,19H,13H2,1-3H3,(H,23,26)/t19-/m0/s1

InChI Key

ABUOYKGUDWOJQM-IBGZPJMESA-N

MDL Number (MFCD)

MFCD12920976

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

399.88

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.993

Distribution Coefficient, logD

3.810

Water Solubility, LogSw

-4.80

Polar Surface Area

56.072

Acid Dissociation Constant (pKa)

13.09

Base Dissociation Constant (pKb)

7.12

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

23.80

D486-0521 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

Neurotransmitter Transporter Inhibitors Library (11024 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Nervous system
Mechanism of action:
  • Epigenetic
Targets:
  • GPCR
  • Ion Channels

References: we are preparing a list of scientific research reports with D486-0521 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D486-0521?
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What is the minimum amount of D486-0521 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D486-0521
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D486-0521
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D486-0521 available by request