D488-0067 Screening compound: N-{2-methyl-3-[(piperidin-1-yl)(pyridin-2-yl)methyl]-1H-indol-5-yl}thiophene-2-carboxamide

D488-0067 Screening compound: N-{2-methyl-3-[(piperidin-1-yl)(pyridin-2-yl)methyl]-1H-indol-5-yl}thiophene-2-carboxamide
D488-0067 Screening compound: N-{2-methyl-3-[(piperidin-1-yl)(pyridin-2-yl)methyl]-1H-indol-5-yl}thiophene-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D488-0067
N-{2-methyl-3-[(piperidin-1-yl)(pyridin-2-yl)methyl]-1H-indol-5-yl}thiophene-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D488-0067

Molecular Formula

C25H26N4OS (C25 H26 N4 OS)

Compound Name

N-{2-methyl-3-[(piperidin-1-yl)(pyridin-2-yl)methyl]-1H-indol-5-yl}thiophene-2-carboxamide

IUPAC name

N-{2-methyl-3-[(piperidin-1-yl)(pyridin-2-yl)methyl]-1H-indol-5-yl}thiophene-2-carboxamide

SMILES

Cc1c(C(c2ncccc2)N2CCCCC2)c(cc(cc2)NC(c3cccs3)=O)c2[nH]1

InChI

InChI=1S/C25H26N4OS/c1-17-23(24(21-8-3-4-12-26-21)29-13-5-2-6-14-29)19-16-18(10-11-20(19)27-17)28-25(30)22-9-7-15-31-22/h3-4,7-12,15-16,24,27H,2,5-6,13-14H2,1H3,(H,28,30)/t24-/m1/s1

InChI Key

DXVSQQGCGWQSDZ-XMMPIXPASA-N

MDL Number (MFCD)

MFCD14832239

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

430.57

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.527

Distribution Coefficient, logD

3.467

Water Solubility, LogSw

-4.16

Polar Surface Area

46.075

Acid Dissociation Constant (pKa)

11.70

Base Dissociation Constant (pKb)

8.42

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

28.00

D488-0067 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with D488-0067 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D488-0067?
Check Price and Availability of D488-0067, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D488-0067 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D488-0067
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D488-0067
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D488-0067 available by request