D494-0487 Screening compound: N-(2-ethylphenyl)-2-{[5-methyl-2-(pyridin-3-yl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl]amino}acetamide

D494-0487 Screening compound: N-(2-ethylphenyl)-2-{[5-methyl-2-(pyridin-3-yl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl]amino}acetamide
D494-0487 Screening compound: N-(2-ethylphenyl)-2-{[5-methyl-2-(pyridin-3-yl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl]amino}acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D494-0487
N-(2-ethylphenyl)-2-{[5-methyl-2-(pyridin-3-yl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl]amino}acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D494-0487

Molecular Formula

C21H21N7O (C21 H21 N7 O)

Compound Name

N-(2-ethylphenyl)-2-{[5-methyl-2-(pyridin-3-yl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl]amino}acetamide

IUPAC name

N-(2-ethylphenyl)-2-{[5-methyl-2-(pyridin-3-yl)-[124]triazolo[15-a]pyrimidin-7-yl]amino}acetamide

SMILES

CCc(cccc1)c1NC(CNc1cc(C)nc2nc(-c3cnccc3)nn12)=O

InChI

InChI=1S/C21H21N7O/c1-3-15-7-4-5-9-17(15)25-19(29)13-23-18-11-14(2)24-21-26-20(27-28(18)21)16-8-6-10-22-12-16/h4-12,23H,3,13H2,1-2H3,(H,25,29)

InChI Key

NCGYPRHENIISJQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27589437

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

387.44

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.612

Distribution Coefficient, logD

2.469

Water Solubility, LogSw

-2.78

Polar Surface Area

73.132

Acid Dissociation Constant (pKa)

13.02

Base Dissociation Constant (pKb)

6.99

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

19.00

D494-0487 in Drug Discovery

Included in Screening Libraries

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with D494-0487 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D494-0487?
Check Price and Availability of D494-0487, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D494-0487 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D494-0487
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D494-0487
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D494-0487 available by request