D503-0345 Screening compound: N-cyclopentyl-2-(4-methoxyphenyl)-3,5-dimethylpyrazolo[1,5-a]pyrimidin-7-amine

D503-0345 Screening compound: N-cyclopentyl-2-(4-methoxyphenyl)-3,5-dimethylpyrazolo[1,5-a]pyrimidin-7-amine
D503-0345 Screening compound: N-cyclopentyl-2-(4-methoxyphenyl)-3,5-dimethylpyrazolo[1,5-a]pyrimidin-7-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound D503-0345
N-cyclopentyl-2-(4-methoxyphenyl)-3,5-dimethylpyrazolo[1,5-a]pyrimidin-7-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D503-0345

Molecular Formula

C20H24N4O (C20 H24 N4 O)

Compound Name

N-cyclopentyl-2-(4-methoxyphenyl)-3,5-dimethylpyrazolo[1,5-a]pyrimidin-7-amine

IUPAC name

N-cyclopentyl-2-(4-methoxyphenyl)-35-dimethylpyrazolo[15-a]pyrimidin-7-amine

SMILES

Cc1c2nc(C)cc(NC3CCCC3)n2nc1-c(cc1)ccc1OC

InChI

InChI=1S/C20H24N4O/c1-13-12-18(22-16-6-4-5-7-16)24-20(21-13)14(2)19(23-24)15-8-10-17(25-3)11-9-15/h8-12,16,22H,4-7H2,1-3H3

InChI Key

CWVOMXYAMAQGSR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD18181034

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

336.44

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.283

Distribution Coefficient, logD

2.323

Water Solubility, LogSw

-4.26

Polar Surface Area

38.731

Acid Dissociation Constant (pKa)

19.59

Base Dissociation Constant (pKb)

9.36

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.00

D503-0345 in Drug Discovery

Included in Screening Libraries

Protein Kinases Inhibitors Library (36801 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Nervous system
  • Cardiovascular
Targets:
  • Kinases
  • Ion Channels

References: we are preparing a list of scientific research reports with D503-0345 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D503-0345?
Check Price and Availability of D503-0345, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D503-0345 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D503-0345
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D503-0345
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D503-0345 available by request