D503-0489 Screening compound: N-(butan-2-yl)-2-(4-chlorophenyl)-3,5-dimethylpyrazolo[1,5-a]pyrimidin-7-amine

D503-0489 Screening compound: N-(butan-2-yl)-2-(4-chlorophenyl)-3,5-dimethylpyrazolo[1,5-a]pyrimidin-7-amine
D503-0489 Screening compound: N-(butan-2-yl)-2-(4-chlorophenyl)-3,5-dimethylpyrazolo[1,5-a]pyrimidin-7-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound D503-0489
N-(butan-2-yl)-2-(4-chlorophenyl)-3,5-dimethylpyrazolo[1,5-a]pyrimidin-7-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D503-0489

Molecular Formula

C18H21ClN4 (C18 H21 ClN4)

Compound Name

N-(butan-2-yl)-2-(4-chlorophenyl)-3,5-dimethylpyrazolo[1,5-a]pyrimidin-7-amine

IUPAC name

N-(butan-2-yl)-2-(4-chlorophenyl)-35-dimethylpyrazolo[15-a]pyrimidin-7-amine

SMILES

CCC(C)Nc1cc(C)nc2c(C)c(-c(cc3)ccc3Cl)nn12

InChI

InChI=1S/C18H21ClN4/c1-5-11(2)20-16-10-12(3)21-18-13(4)17(22-23(16)18)14-6-8-15(19)9-7-14/h6-11,20H,5H2,1-4H3/t11-/m0/s1

InChI Key

FPRRLMTYMRKRHT-NSHDSACASA-N

MDL Number (MFCD)

MFCD18181101

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

328.84

Hydrogen Bond Acceptors Count

2.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

4.554

Distribution Coefficient, logD

2.594

Water Solubility, LogSw

-4.66

Polar Surface Area

30.809

Acid Dissociation Constant (pKa)

19.59

Base Dissociation Constant (pKb)

9.36

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

33.30

D503-0489 in Drug Discovery

Included in Screening Libraries

CNS BBB Library (22607 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

SmartTM Library (51161 compounds)

Targeted Diversity Library (40567 compounds)

Ion Channels Focused Library (26372 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Nervous system
  • Cardiovascular
Targets:
  • Kinases
  • Ion Channels
Agro:
  • Agro

References: we are preparing a list of scientific research reports with D503-0489 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D503-0489?
Check Price and Availability of D503-0489, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D503-0489 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D503-0489
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D503-0489
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D503-0489 available by request