D517-1147 Screening compound: 6-(2,5-dimethoxyphenyl)-5-(2-oxo-2,3-dihydro-1H-indol-3-yl)-1H,2H,3H,4H,7H-pyrrolo[2,3-d]pyrimidine-2,4-dione

D517-1147 Screening compound: 6-(2,5-dimethoxyphenyl)-5-(2-oxo-2,3-dihydro-1H-indol-3-yl)-1H,2H,3H,4H,7H-pyrrolo[2,3-d]pyrimidine-2,4-dione
D517-1147 Screening compound: 6-(2,5-dimethoxyphenyl)-5-(2-oxo-2,3-dihydro-1H-indol-3-yl)-1H,2H,3H,4H,7H-pyrrolo[2,3-d]pyrimidine-2,4-dione alternative view

Chemical Structure Depiction of ChemDiv screening compound D517-1147
6-(2,5-dimethoxyphenyl)-5-(2-oxo-2,3-dihydro-1H-indol-3-yl)-1H,2H,3H,4H,7H-pyrrolo[2,3-d]pyrimidine-2,4-dione

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D517-1147

Molecular Formula

C22H18N4O5 (C22 H18 N4 O5)

Compound Name

6-(2,5-dimethoxyphenyl)-5-(2-oxo-2,3-dihydro-1H-indol-3-yl)-1H,2H,3H,4H,7H-pyrrolo[2,3-d]pyrimidine-2,4-dione

IUPAC name

6-(25-dimethoxyphenyl)-5-(2-oxo-23-dihydro-1H-indol-3-yl)-1H2H3H4H7H-pyrrolo[23-d]pyrimidine-24-dione

SMILES

COc(cc1)cc(-c([nH]2)c(C(c(cccc3)c3N3)C3=O)c(C(N3)=O)c2NC3=O)c1OC

InChI

InChI=1S/C22H18N4O5/c1-30-10-7-8-14(31-2)12(9-10)18-16(17-19(24-18)25-22(29)26-21(17)28)15-11-5-3-4-6-13(11)23-20(15)27/h3-9,15H,1-2H3,(H,23,27)(H3,24,25,26,28,29)/t15-/m0/s1

InChI Key

RJLROCJRYBETKD-HNNXBMFYSA-N

MDL Number (MFCD)

MFCD27590638

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

418.41

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

4.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

2.189

Distribution Coefficient, logD

1.891

Water Solubility, LogSw

-3.13

Polar Surface Area

99.976

Acid Dissociation Constant (pKa)

7.41

Base Dissociation Constant (pKb)

-0.40

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

13.60

D517-1147 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

C-Met Library (15277 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Kinases
  • Kinases
  • Phosphatases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with D517-1147 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D517-1147?
Check Price and Availability of D517-1147, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D517-1147 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D517-1147
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D517-1147
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D517-1147 available by request