D520-0499 Screening compound: N-(2,4-difluorophenyl)-7-(3,4-dimethoxyphenyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide

D520-0499 Screening compound: N-(2,4-difluorophenyl)-7-(3,4-dimethoxyphenyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide
D520-0499 Screening compound: N-(2,4-difluorophenyl)-7-(3,4-dimethoxyphenyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D520-0499
N-(2,4-difluorophenyl)-7-(3,4-dimethoxyphenyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D520-0499

Molecular Formula

C21H16F2N4O3 (C21 H16 F2 N4 O3)

Compound Name

N-(2,4-difluorophenyl)-7-(3,4-dimethoxyphenyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide

IUPAC name

N-(24-difluorophenyl)-7-(34-dimethoxyphenyl)pyrazolo[15-a]pyrimidine-2-carboxamide

SMILES

COc(ccc(-c1ccnc2cc(C(Nc(ccc(F)c3)c3F)=O)nn12)c1)c1OC

InChI

InChI=1S/C21H16F2N4O3/c1-29-18-6-3-12(9-19(18)30-2)17-7-8-24-20-11-16(26-27(17)20)21(28)25-15-5-4-13(22)10-14(15)23/h3-11H,1-2H3,(H,25,28)

InChI Key

NLQJCGDLLVTQNL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27590671

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

410.38

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.379

Distribution Coefficient, logD

3.254

Water Solubility, LogSw

-3.75

Polar Surface Area

56.484

Acid Dissociation Constant (pKa)

7.88

Base Dissociation Constant (pKb)

1.43

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

9.50

D520-0499 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer

References: we are preparing a list of scientific research reports with D520-0499 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D520-0499?
Check Price and Availability of D520-0499, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D520-0499 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D520-0499
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D520-0499
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D520-0499 available by request