D524-2486 Screening compound: N-{5,6-dimethyl-7-oxo-4H,7H-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl}-4-fluoro-N-[(4-methylphenyl)methyl]benzamide

D524-2486 Screening compound: N-{5,6-dimethyl-7-oxo-4H,7H-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl}-4-fluoro-N-[(4-methylphenyl)methyl]benzamide
D524-2486 Screening compound: N-{5,6-dimethyl-7-oxo-4H,7H-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl}-4-fluoro-N-[(4-methylphenyl)methyl]benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D524-2486
N-{5,6-dimethyl-7-oxo-4H,7H-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl}-4-fluoro-N-[(4-methylphenyl)methyl]benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D524-2486

Molecular Formula

C22H20FN5O2 (C22 H20 FN5 O2)

Compound Name

N-{5,6-dimethyl-7-oxo-4H,7H-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl}-4-fluoro-N-[(4-methylphenyl)methyl]benzamide

IUPAC name

N-{56-dimethyl-7-oxo-4H7H-[124]triazolo[15-a]pyrimidin-2-yl}-4-fluoro-N-[(4-methylphenyl)methyl]benzamide

SMILES

Cc1ccc(CN(C(c(cc2)ccc2F)=O)c(nc2NC(C)=C3C)nn2C3=O)cc1

InChI

InChI=1S/C22H20FN5O2/c1-13-4-6-16(7-5-13)12-27(20(30)17-8-10-18(23)11-9-17)22-25-21-24-15(3)14(2)19(29)28(21)26-22/h4-11H,12H2,1-3H3,(H,24,25,26)

InChI Key

IJTMZFOBAIIAIE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27590784

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

405.43

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.927

Distribution Coefficient, logD

3.547

Water Solubility, LogSw

-3.97

Polar Surface Area

64.801

Acid Dissociation Constant (pKa)

7.25

Base Dissociation Constant (pKb)

-3.20

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

18.20

D524-2486 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Type II Kinase Inhibitors Library (6956 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Digestive system
  • Hemic and lymphatic
  • Endocrine
Targets:
  • Kinases
  • Kinases

References: we are preparing a list of scientific research reports with D524-2486 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D524-2486?
Check Price and Availability of D524-2486, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D524-2486 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D524-2486
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D524-2486
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D524-2486 available by request