D567-0145 Screening compound: 1-(4-{[1,3]oxazolo[5,4-b]pyridin-2-yl}piperazin-1-yl)-2-phenoxyethan-1-one

D567-0145 Screening compound: 1-(4-{[1,3]oxazolo[5,4-b]pyridin-2-yl}piperazin-1-yl)-2-phenoxyethan-1-one
D567-0145 Screening compound: 1-(4-{[1,3]oxazolo[5,4-b]pyridin-2-yl}piperazin-1-yl)-2-phenoxyethan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound D567-0145
1-(4-{[1,3]oxazolo[5,4-b]pyridin-2-yl}piperazin-1-yl)-2-phenoxyethan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D567-0145

Molecular Formula

C18H18N4O3 (C18 H18 N4 O3)

Compound Name

1-(4-{[1,3]oxazolo[5,4-b]pyridin-2-yl}piperazin-1-yl)-2-phenoxyethan-1-one

IUPAC name

1-(4-{[13]oxazolo[54-b]pyridin-2-yl}piperazin-1-yl)-2-phenoxyethan-1-one

SMILES

O=C(COc1ccccc1)N(CC1)CCN1c1nc(cccn2)c2o1

InChI

InChI=1S/C18H18N4O3/c23-16(13-24-14-5-2-1-3-6-14)21-9-11-22(12-10-21)18-20-15-7-4-8-19-17(15)25-18/h1-8H,9-13H2

InChI Key

SXEGMPRNAMZBDP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14833621

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

338.37

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

1.563

Distribution Coefficient, logD

1.563

Water Solubility, LogSw

-1.49

Polar Surface Area

53.493

Acid Dissociation Constant (pKa)

23.11

Base Dissociation Constant (pKb)

3.56

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.80

D567-0145 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Protein-Protein Interaction Library (218420 compounds)

Akt-Targeted Library (14764 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Immune system
  • Nervous system
  • Cardiovascular
Targets:
  • GPCR
  • Kinases
  • Ion Channels
Mechanism of action:
  • Receptor's ligands
  • PPI modulators
  • Receptor's ligands

References: we are preparing a list of scientific research reports with D567-0145 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D567-0145?
Check Price and Availability of D567-0145, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D567-0145 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D567-0145
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D567-0145
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D567-0145 available by request