D573-0276 Screening compound: 4-methyl-N-(4-methylphenyl)-6-{4-[4-(trifluoromethyl)benzoyl]piperazin-1-yl}pyrimidin-2-amine

D573-0276 Screening compound: 4-methyl-N-(4-methylphenyl)-6-{4-[4-(trifluoromethyl)benzoyl]piperazin-1-yl}pyrimidin-2-amine
D573-0276 Screening compound: 4-methyl-N-(4-methylphenyl)-6-{4-[4-(trifluoromethyl)benzoyl]piperazin-1-yl}pyrimidin-2-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound D573-0276
4-methyl-N-(4-methylphenyl)-6-{4-[4-(trifluoromethyl)benzoyl]piperazin-1-yl}pyrimidin-2-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D573-0276

Molecular Formula

C24H24F3N5O (C24 H24 F3 N5 O)

Compound Name

4-methyl-N-(4-methylphenyl)-6-{4-[4-(trifluoromethyl)benzoyl]piperazin-1-yl}pyrimidin-2-amine

IUPAC name

4-methyl-N-(4-methylphenyl)-6-{4-[4-(trifluoromethyl)benzoyl]piperazin-1-yl}pyrimidin-2-amine

SMILES

Cc(cc1)ccc1Nc1nc(C)cc(N(CC2)CCN2C(c2ccc(C(F)(F)F)cc2)=O)n1

InChI

InChI=1S/C24H24F3N5O/c1-16-3-9-20(10-4-16)29-23-28-17(2)15-21(30-23)31-11-13-32(14-12-31)22(33)18-5-7-19(8-6-18)24(25,26)27/h3-10,15H,11-14H2,1-2H3,(H,28,29,30)

InChI Key

BGNSJXRPOKJRRD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27593155

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

455.48

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.531

Distribution Coefficient, logD

5.471

Water Solubility, LogSw

-5.43

Polar Surface Area

48.035

Acid Dissociation Constant (pKa)

18.25

Base Dissociation Constant (pKb)

6.57

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

29.20

D573-0276 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with D573-0276 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D573-0276?
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What is the minimum amount of D573-0276 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D573-0276
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D573-0276
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D573-0276 available by request