D600-0218 Screening compound: 3-[3-(phenylamino)imidazo[1,2-a]pyrazin-2-yl]phenol

D600-0218 Screening compound: 3-[3-(phenylamino)imidazo[1,2-a]pyrazin-2-yl]phenol
D600-0218 Screening compound: 3-[3-(phenylamino)imidazo[1,2-a]pyrazin-2-yl]phenol alternative view

Chemical Structure Depiction of ChemDiv screening compound D600-0218
3-[3-(phenylamino)imidazo[1,2-a]pyrazin-2-yl]phenol

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D600-0218

Molecular Formula

C18H14N4O (C18 H14 N4 O)

Compound Name

3-[3-(phenylamino)imidazo[1,2-a]pyrazin-2-yl]phenol

IUPAC name

3-[3-(phenylamino)imidazo[12-a]pyrazin-2-yl]phenol

SMILES

Oc1cc(-c2c(Nc3ccccc3)n(ccnc3)c3n2)ccc1

InChI

InChI=1S/C18H14N4O/c23-15-8-4-5-13(11-15)17-18(20-14-6-2-1-3-7-14)22-10-9-19-12-16(22)21-17/h1-12,20,23H

InChI Key

BDUVMLAZEJLAGB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD09694711

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

302.34

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.126

Distribution Coefficient, logD

3.124

Water Solubility, LogSw

-2.96

Polar Surface Area

44.814

Acid Dissociation Constant (pKa)

9.80

Base Dissociation Constant (pKb)

4.46

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

0.00

D600-0218 in Drug Discovery

Included in Screening Libraries

Protein Kinases Inhibitors Library (36801 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Targeted Diversity Library (40567 compounds)

Carbonic Anhydrase II Library (4939 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with D600-0218 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D600-0218?
Check Price and Availability of D600-0218, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D600-0218 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D600-0218
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D600-0218
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D600-0218 available by request