D600-0453 Screening compound: N-(2-methoxyphenyl)-2-[4-(morpholin-4-yl)phenyl]imidazo[1,2-a]pyrazin-3-amine

D600-0453 Screening compound: N-(2-methoxyphenyl)-2-[4-(morpholin-4-yl)phenyl]imidazo[1,2-a]pyrazin-3-amine
D600-0453 Screening compound: N-(2-methoxyphenyl)-2-[4-(morpholin-4-yl)phenyl]imidazo[1,2-a]pyrazin-3-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound D600-0453
N-(2-methoxyphenyl)-2-[4-(morpholin-4-yl)phenyl]imidazo[1,2-a]pyrazin-3-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D600-0453

Molecular Formula

C23H23N5O2 (C23 H23 N5 O2)

Compound Name

N-(2-methoxyphenyl)-2-[4-(morpholin-4-yl)phenyl]imidazo[1,2-a]pyrazin-3-amine

IUPAC name

N-(2-methoxyphenyl)-2-[4-(morpholin-4-yl)phenyl]imidazo[12-a]pyrazin-3-amine

SMILES

COc(cccc1)c1Nc1c(-c(cc2)ccc2N2CCOCC2)nc2n1ccnc2

InChI

InChI=1S/C23H23N5O2/c1-29-20-5-3-2-4-19(20)25-23-22(26-21-16-24-10-11-28(21)23)17-6-8-18(9-7-17)27-12-14-30-15-13-27/h2-11,16,25H,12-15H2,1H3

InChI Key

KXWYUIJGVODWBH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27594538

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

401.47

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.414

Distribution Coefficient, logD

3.413

Water Solubility, LogSw

-3.33

Polar Surface Area

45.490

Acid Dissociation Constant (pKa)

18.61

Base Dissociation Constant (pKb)

4.20

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

21.70

D600-0453 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Anti-Inflammatory Library (24602 compounds)

PI3K-Targeted Library (17255 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with D600-0453 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D600-0453?
Check Price and Availability of D600-0453, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D600-0453 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D600-0453
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D600-0453
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D600-0453 available by request