D647-0146 Screening compound: 5-(4-chlorophenyl)-N-[2-(2,5-dimethoxyphenyl)-2-(piperidin-1-yl)ethyl]-1,2-oxazole-3-carboxamide

D647-0146 Screening compound: 5-(4-chlorophenyl)-N-[2-(2,5-dimethoxyphenyl)-2-(piperidin-1-yl)ethyl]-1,2-oxazole-3-carboxamide
D647-0146 Screening compound: 5-(4-chlorophenyl)-N-[2-(2,5-dimethoxyphenyl)-2-(piperidin-1-yl)ethyl]-1,2-oxazole-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D647-0146
5-(4-chlorophenyl)-N-[2-(2,5-dimethoxyphenyl)-2-(piperidin-1-yl)ethyl]-1,2-oxazole-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D647-0146

Molecular Formula

C25H28ClN3O4 (C25 H28 ClN3 O4)

Compound Name

5-(4-chlorophenyl)-N-[2-(2,5-dimethoxyphenyl)-2-(piperidin-1-yl)ethyl]-1,2-oxazole-3-carboxamide

IUPAC name

5-(4-chlorophenyl)-N-[2-(25-dimethoxyphenyl)-2-(piperidin-1-yl)ethyl]-12-oxazole-3-carboxamide

SMILES

COc(cc1)cc(C(CNC(c2noc(-c(cc3)ccc3Cl)c2)=O)N2CCCCC2)c1OC

InChI

InChI=1S/C25H28ClN3O4/c1-31-19-10-11-23(32-2)20(14-19)22(29-12-4-3-5-13-29)16-27-25(30)21-15-24(33-28-21)17-6-8-18(26)9-7-17/h6-11,14-15,22H,3-5,12-13,16H2,1-2H3,(H,27,30)/t22-/m0/s1

InChI Key

QTVQYQGHFGASNB-QFIPXVFZSA-N

MDL Number (MFCD)

MFCD18078650

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

469.97

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.073

Distribution Coefficient, logD

3.428

Water Solubility, LogSw

-5.42

Polar Surface Area

64.351

Acid Dissociation Constant (pKa)

13.09

Base Dissociation Constant (pKb)

9.04

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

36.00

D647-0146 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Neurotransmitter Transporter Inhibitors Library (11024 compounds)

Nucleic Acid Ligands (8311 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Infections
  • Cancer
  • Musculoskeletal
  • Nervous system
  • Hemic and lymphatic
  • Immune system
Targets:
  • GPCR
  • Ion Channels

References: we are preparing a list of scientific research reports with D647-0146 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D647-0146?
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What is the minimum amount of D647-0146 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D647-0146
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D647-0146
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D647-0146 available by request