D667-0035 Screening compound: 4-bromo-2-{3-[(3,4-dimethoxyphenyl)amino]imidazo[1,2-a]pyrazin-2-yl}phenol

D667-0035 Screening compound: 4-bromo-2-{3-[(3,4-dimethoxyphenyl)amino]imidazo[1,2-a]pyrazin-2-yl}phenol
D667-0035 Screening compound: 4-bromo-2-{3-[(3,4-dimethoxyphenyl)amino]imidazo[1,2-a]pyrazin-2-yl}phenol alternative view

Chemical Structure Depiction of ChemDiv screening compound D667-0035
4-bromo-2-{3-[(3,4-dimethoxyphenyl)amino]imidazo[1,2-a]pyrazin-2-yl}phenol

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D667-0035

Molecular Formula

C20H17BrN4O3 (C20 H17 BrN4 O3)

Compound Name

4-bromo-2-{3-[(3,4-dimethoxyphenyl)amino]imidazo[1,2-a]pyrazin-2-yl}phenol

IUPAC name

4-bromo-2-{3-[(34-dimethoxyphenyl)amino]imidazo[12-a]pyrazin-2-yl}phenol

SMILES

COc(ccc(Nc1c(-c(cc(cc2)Br)c2O)nc2n1ccnc2)c1)c1OC

InChI

InChI=1S/C20H17BrN4O3/c1-27-16-6-4-13(10-17(16)28-2)23-20-19(14-9-12(21)3-5-15(14)26)24-18-11-22-7-8-25(18)20/h3-11,23,26H,1-2H3

InChI Key

CBTYHCWHDLMDFP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27595273

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

441.28

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.318

Distribution Coefficient, logD

4.298

Water Solubility, LogSw

-3.87

Polar Surface Area

59.006

Acid Dissociation Constant (pKa)

8.74

Base Dissociation Constant (pKb)

4.20

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

10.00

D667-0035 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

Antimitotic Tubulin Library (17355 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Mechanism of action:
  • Epigenetic
  • PPI modulators

References: we are preparing a list of scientific research reports with D667-0035 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D667-0035?
Check Price and Availability of D667-0035, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D667-0035 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D667-0035
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D667-0035
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D667-0035 available by request