D677-0376 Screening compound: 2-cyclopropyl-N-{[5-(furan-2-yl)-1,2,4-oxadiazol-3-yl]methyl}acetamide

D677-0376 Screening compound: 2-cyclopropyl-N-{[5-(furan-2-yl)-1,2,4-oxadiazol-3-yl]methyl}acetamide
D677-0376 Screening compound: 2-cyclopropyl-N-{[5-(furan-2-yl)-1,2,4-oxadiazol-3-yl]methyl}acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D677-0376
2-cyclopropyl-N-{[5-(furan-2-yl)-1,2,4-oxadiazol-3-yl]methyl}acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D677-0376

Molecular Formula

C12H13N3O3 (C12 H13 N3 O3)

Compound Name

2-cyclopropyl-N-{[5-(furan-2-yl)-1,2,4-oxadiazol-3-yl]methyl}acetamide

IUPAC name

2-cyclopropyl-N-{[5-(furan-2-yl)-124-oxadiazol-3-yl]methyl}acetamide

SMILES

O=C(CC1CC1)NCc1noc(-c2ccco2)n1

InChI

InChI=1S/C12H13N3O3/c16-11(6-8-3-4-8)13-7-10-14-12(18-15-10)9-2-1-5-17-9/h1-2,5,8H,3-4,6-7H2,(H,13,16)

InChI Key

GULLSWFIAGKSNR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27595837

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

247.25

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

1.350

Distribution Coefficient, logD

1.350

Water Solubility, LogSw

-1.69

Polar Surface Area

66.208

Acid Dissociation Constant (pKa)

13.99

Base Dissociation Constant (pKb)

-4.93

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

41.70

D677-0376 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Soluble Diversity Library (15920 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with D677-0376 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D677-0376?
Check Price and Availability of D677-0376, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D677-0376 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D677-0376
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D677-0376
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D677-0376 available by request