D694-0229 Screening compound: N-(2,4-difluorophenyl)-2-[1,7-dimethyl-2,4-dioxo-5-(piperidine-1-carbonyl)-1H,2H,3H,4H-pyrido[2,3-d]pyrimidin-3-yl]acetamide

D694-0229 Screening compound: N-(2,4-difluorophenyl)-2-[1,7-dimethyl-2,4-dioxo-5-(piperidine-1-carbonyl)-1H,2H,3H,4H-pyrido[2,3-d]pyrimidin-3-yl]acetamide
D694-0229 Screening compound: N-(2,4-difluorophenyl)-2-[1,7-dimethyl-2,4-dioxo-5-(piperidine-1-carbonyl)-1H,2H,3H,4H-pyrido[2,3-d]pyrimidin-3-yl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D694-0229
N-(2,4-difluorophenyl)-2-[1,7-dimethyl-2,4-dioxo-5-(piperidine-1-carbonyl)-1H,2H,3H,4H-pyrido[2,3-d]pyrimidin-3-yl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D694-0229

Molecular Formula

C23H23F2N5O4 (C23 H23 F2 N5 O4)

Compound Name

N-(2,4-difluorophenyl)-2-[1,7-dimethyl-2,4-dioxo-5-(piperidine-1-carbonyl)-1H,2H,3H,4H-pyrido[2,3-d]pyrimidin-3-yl]acetamide

IUPAC name

N-(24-difluorophenyl)-2-[17-dimethyl-24-dioxo-5-(piperidine-1-carbonyl)-1H2H3H4H-pyrido[23-d]pyrimidin-3-yl]acetamide

SMILES

Cc(cc1C(N2CCCCC2)=O)nc(N(C)C(N2CC(Nc(ccc(F)c3)c3F)=O)=O)c1C2=O

InChI

InChI=1S/C23H23F2N5O4/c1-13-10-15(21(32)29-8-4-3-5-9-29)19-20(26-13)28(2)23(34)30(22(19)33)12-18(31)27-17-7-6-14(24)11-16(17)25/h6-7,10-11H,3-5,8-9,12H2,1-2H3,(H,27,31)

InChI Key

GVEPHWRAIWLZGH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27596639

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

471.46

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

2.409

Distribution Coefficient, logD

2.405

Water Solubility, LogSw

-3.15

Polar Surface Area

80.109

Acid Dissociation Constant (pKa)

9.48

Base Dissociation Constant (pKb)

2.86

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

34.80

D694-0229 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Hsp90-Targeted Library (11355 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Targeted Diversity Library (40567 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic
  • PPI modulators
Agro:
  • Agro

References: we are preparing a list of scientific research reports with D694-0229 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D694-0229?
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What is the minimum amount of D694-0229 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D694-0229
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D694-0229
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D694-0229 available by request