D703-0018 Screening compound: N-[4-ethyl-5-(3-phenyl-1,2,4-oxadiazol-5-yl)-1,3-thiazol-2-yl]-4-methylbenzamide

D703-0018 Screening compound: N-[4-ethyl-5-(3-phenyl-1,2,4-oxadiazol-5-yl)-1,3-thiazol-2-yl]-4-methylbenzamide
D703-0018 Screening compound: N-[4-ethyl-5-(3-phenyl-1,2,4-oxadiazol-5-yl)-1,3-thiazol-2-yl]-4-methylbenzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D703-0018
N-[4-ethyl-5-(3-phenyl-1,2,4-oxadiazol-5-yl)-1,3-thiazol-2-yl]-4-methylbenzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D703-0018

Molecular Formula

C21H18N4O2S (C21 H18 N4 O2 S)

Compound Name

N-[4-ethyl-5-(3-phenyl-1,2,4-oxadiazol-5-yl)-1,3-thiazol-2-yl]-4-methylbenzamide

IUPAC name

N-[4-ethyl-5-(3-phenyl-124-oxadiazol-5-yl)-13-thiazol-2-yl]-4-methylbenzamide

SMILES

CCc1c(-c2nc(-c3ccccc3)no2)sc(NC(c2ccc(C)cc2)=O)n1

InChI

InChI=1S/C21H18N4O2S/c1-3-16-17(20-23-18(25-27-20)14-7-5-4-6-8-14)28-21(22-16)24-19(26)15-11-9-13(2)10-12-15/h4-12H,3H2,1-2H3,(H,22,24,26)

InChI Key

DRGYEDHUBIWZQJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27597000

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

390.47

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.727

Distribution Coefficient, logD

5.690

Water Solubility, LogSw

-5.55

Polar Surface Area

66.047

Acid Dissociation Constant (pKa)

8.45

Base Dissociation Constant (pKb)

1.26

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

14.30

D703-0018 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

Anticancer Library (62698 compounds)

C-Met Library (15277 compounds)

GPCR Targeted Library (31838 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Type II Kinase Inhibitors Library (6956 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Digestive system
  • Hemic and lymphatic
  • Endocrine
Targets:
  • Kinases
  • Kinases
  • GPCR
  • Kinases
  • Kinases
Mechanism of action:
  • Receptor's ligands
  • Receptor's ligands

References: we are preparing a list of scientific research reports with D703-0018 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D703-0018?
Check Price and Availability of D703-0018, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D703-0018 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D703-0018
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D703-0018
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D703-0018 available by request