D703-0045 Screening compound: N-[4-ethyl-5-(3-phenyl-1,2,4-oxadiazol-5-yl)-1,3-thiazol-2-yl]-2,2-dimethylpropanamide

D703-0045 Screening compound: N-[4-ethyl-5-(3-phenyl-1,2,4-oxadiazol-5-yl)-1,3-thiazol-2-yl]-2,2-dimethylpropanamide
D703-0045 Screening compound: N-[4-ethyl-5-(3-phenyl-1,2,4-oxadiazol-5-yl)-1,3-thiazol-2-yl]-2,2-dimethylpropanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D703-0045
N-[4-ethyl-5-(3-phenyl-1,2,4-oxadiazol-5-yl)-1,3-thiazol-2-yl]-2,2-dimethylpropanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D703-0045

Molecular Formula

C18H20N4O2S (C18 H20 N4 O2 S)

Compound Name

N-[4-ethyl-5-(3-phenyl-1,2,4-oxadiazol-5-yl)-1,3-thiazol-2-yl]-2,2-dimethylpropanamide

IUPAC name

N-[4-ethyl-5-(3-phenyl-124-oxadiazol-5-yl)-13-thiazol-2-yl]-22-dimethylpropanamide

SMILES

CCc1c(-c2nc(-c3ccccc3)no2)sc(NC(C(C)(C)C)=O)n1

InChI

InChI=1S/C18H20N4O2S/c1-5-12-13(25-17(19-12)21-16(23)18(2,3)4)15-20-14(22-24-15)11-9-7-6-8-10-11/h6-10H,5H2,1-4H3,(H,19,21,23)

InChI Key

FJTNBXAPMNMQBH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27597010

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

356.45

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.894

Distribution Coefficient, logD

4.891

Water Solubility, LogSw

-4.59

Polar Surface Area

66.319

Acid Dissociation Constant (pKa)

9.56

Base Dissociation Constant (pKb)

1.72

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.30

D703-0045 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

C-Met Library (15277 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Nervous system
  • Cardiovascular
Targets:
  • Kinases
  • Kinases
  • Ion Channels
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with D703-0045 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D703-0045?
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What is the minimum amount of D703-0045 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D703-0045
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D703-0045
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D703-0045 available by request