D703-0105 Screening compound: 3-methoxy-N-[5-(3-phenyl-1,2,4-oxadiazol-5-yl)-4-(propan-2-yl)-1,3-thiazol-2-yl]benzamide

D703-0105 Screening compound: 3-methoxy-N-[5-(3-phenyl-1,2,4-oxadiazol-5-yl)-4-(propan-2-yl)-1,3-thiazol-2-yl]benzamide
D703-0105 Screening compound: 3-methoxy-N-[5-(3-phenyl-1,2,4-oxadiazol-5-yl)-4-(propan-2-yl)-1,3-thiazol-2-yl]benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D703-0105
3-methoxy-N-[5-(3-phenyl-1,2,4-oxadiazol-5-yl)-4-(propan-2-yl)-1,3-thiazol-2-yl]benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D703-0105

Molecular Formula

C22H20N4O3S (C22 H20 N4 O3 S)

Compound Name

3-methoxy-N-[5-(3-phenyl-1,2,4-oxadiazol-5-yl)-4-(propan-2-yl)-1,3-thiazol-2-yl]benzamide

IUPAC name

3-methoxy-N-[5-(3-phenyl-124-oxadiazol-5-yl)-4-(propan-2-yl)-13-thiazol-2-yl]benzamide

SMILES

CC(C)c1c(-c2nc(-c3ccccc3)no2)sc(NC(c2cc(OC)ccc2)=O)n1

InChI

InChI=1S/C22H20N4O3S/c1-13(2)17-18(21-24-19(26-29-21)14-8-5-4-6-9-14)30-22(23-17)25-20(27)15-10-7-11-16(12-15)28-3/h4-13H,1-3H3,(H,23,25,27)

InChI Key

VWBKRYFAXLAHRD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27597022

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

420.49

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

6.208

Distribution Coefficient, logD

6.201

Water Solubility, LogSw

-5.55

Polar Surface Area

73.096

Acid Dissociation Constant (pKa)

9.18

Base Dissociation Constant (pKb)

1.51

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

18.20

D703-0105 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

C-Met Library (15277 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Type II Kinase Inhibitors Library (6956 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Digestive system
  • Hemic and lymphatic
  • Endocrine
Targets:
  • Kinases
  • Kinases
  • Kinases
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with D703-0105 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D703-0105?
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What is the minimum amount of D703-0105 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D703-0105
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D703-0105
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D703-0105 available by request