D703-0154 Screening compound: 4-methoxy-N-{4-methyl-5-[3-(3-methylphenyl)-1,2,4-oxadiazol-5-yl]-1,3-thiazol-2-yl}benzamide

D703-0154 Screening compound: 4-methoxy-N-{4-methyl-5-[3-(3-methylphenyl)-1,2,4-oxadiazol-5-yl]-1,3-thiazol-2-yl}benzamide
D703-0154 Screening compound: 4-methoxy-N-{4-methyl-5-[3-(3-methylphenyl)-1,2,4-oxadiazol-5-yl]-1,3-thiazol-2-yl}benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D703-0154
4-methoxy-N-{4-methyl-5-[3-(3-methylphenyl)-1,2,4-oxadiazol-5-yl]-1,3-thiazol-2-yl}benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D703-0154

Molecular Formula

C21H18N4O3S (C21 H18 N4 O3 S)

Compound Name

4-methoxy-N-{4-methyl-5-[3-(3-methylphenyl)-1,2,4-oxadiazol-5-yl]-1,3-thiazol-2-yl}benzamide

IUPAC name

4-methoxy-N-{4-methyl-5-[3-(3-methylphenyl)-124-oxadiazol-5-yl]-13-thiazol-2-yl}benzamide

SMILES

Cc1c(-c2nc(-c3cc(C)ccc3)no2)sc(NC(c(cc2)ccc2OC)=O)n1

InChI

InChI=1S/C21H18N4O3S/c1-12-5-4-6-15(11-12)18-23-20(28-25-18)17-13(2)22-21(29-17)24-19(26)14-7-9-16(27-3)10-8-14/h4-11H,1-3H3,(H,22,24,26)

InChI Key

FVOUYRIDRHFTLM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27597037

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

406.47

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.353

Distribution Coefficient, logD

5.338

Water Solubility, LogSw

-5.46

Polar Surface Area

72.902

Acid Dissociation Constant (pKa)

8.84

Base Dissociation Constant (pKb)

1.02

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

14.30

D703-0154 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

C-Met Library (15277 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Ion Channels Focused Library (26372 compounds)

Type II Kinase Inhibitors Library (6956 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Nervous system
  • Cardiovascular
  • Digestive system
  • Hemic and lymphatic
  • Endocrine
Targets:
  • Kinases
  • Kinases
  • Kinases
  • Ion Channels
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with D703-0154 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D703-0154?
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What is the minimum amount of D703-0154 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D703-0154
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D703-0154
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D703-0154 available by request