D703-0172 Screening compound: N-{4-methyl-5-[3-(3-methylphenyl)-1,2,4-oxadiazol-5-yl]-1,3-thiazol-2-yl}furan-2-carboxamide

D703-0172 Screening compound: N-{4-methyl-5-[3-(3-methylphenyl)-1,2,4-oxadiazol-5-yl]-1,3-thiazol-2-yl}furan-2-carboxamide
D703-0172 Screening compound: N-{4-methyl-5-[3-(3-methylphenyl)-1,2,4-oxadiazol-5-yl]-1,3-thiazol-2-yl}furan-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D703-0172
N-{4-methyl-5-[3-(3-methylphenyl)-1,2,4-oxadiazol-5-yl]-1,3-thiazol-2-yl}furan-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D703-0172

Molecular Formula

C18H14N4O3S (C18 H14 N4 O3 S)

Compound Name

N-{4-methyl-5-[3-(3-methylphenyl)-1,2,4-oxadiazol-5-yl]-1,3-thiazol-2-yl}furan-2-carboxamide

IUPAC name

N-{4-methyl-5-[3-(3-methylphenyl)-124-oxadiazol-5-yl]-13-thiazol-2-yl}furan-2-carboxamide

SMILES

Cc1c(-c2nc(-c3cc(C)ccc3)no2)sc(NC(c2ccco2)=O)n1

InChI

InChI=1S/C18H14N4O3S/c1-10-5-3-6-12(9-10)15-20-17(25-22-15)14-11(2)19-18(26-14)21-16(23)13-7-4-8-24-13/h3-9H,1-2H3,(H,19,21,23)

InChI Key

ZEIGHRUCVWVDJD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27597044

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

366.4

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.643

Distribution Coefficient, logD

4.632

Water Solubility, LogSw

-4.50

Polar Surface Area

73.937

Acid Dissociation Constant (pKa)

8.98

Base Dissociation Constant (pKb)

0.51

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

11.10

D703-0172 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

C-Met Library (15277 compounds)

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • Kinases
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • Receptor's ligands

References: we are preparing a list of scientific research reports with D703-0172 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D703-0172?
Check Price and Availability of D703-0172, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D703-0172 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D703-0172
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D703-0172
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D703-0172 available by request