D703-0224 Screening compound: N-{4-methyl-5-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]-1,3-thiazol-2-yl}thiophene-2-carboxamide

D703-0224 Screening compound: N-{4-methyl-5-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]-1,3-thiazol-2-yl}thiophene-2-carboxamide
D703-0224 Screening compound: N-{4-methyl-5-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]-1,3-thiazol-2-yl}thiophene-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D703-0224
N-{4-methyl-5-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]-1,3-thiazol-2-yl}thiophene-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D703-0224

Molecular Formula

C18H14N4O2S2 (C18 H14 N4 O2 S2)

Compound Name

N-{4-methyl-5-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]-1,3-thiazol-2-yl}thiophene-2-carboxamide

IUPAC name

N-{4-methyl-5-[3-(4-methylphenyl)-124-oxadiazol-5-yl]-13-thiazol-2-yl}thiophene-2-carboxamide

SMILES

Cc1c(-c2nc(-c3ccc(C)cc3)no2)sc(NC(c2cccs2)=O)n1

InChI

InChI=1S/C18H14N4O2S2/c1-10-5-7-12(8-6-10)15-20-17(24-22-15)14-11(2)19-18(26-14)21-16(23)13-4-3-9-25-13/h3-9H,1-2H3,(H,19,21,23)

InChI Key

IDGQBIMFCNQCFJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27597066

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

382.47

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.338

Distribution Coefficient, logD

5.334

Water Solubility, LogSw

-5.33

Polar Surface Area

66.377

Acid Dissociation Constant (pKa)

9.43

Base Dissociation Constant (pKb)

0.99

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

11.10

D703-0224 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

Anticancer Library (62698 compounds)

C-Met Library (15277 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with D703-0224 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D703-0224?
Check Price and Availability of D703-0224, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D703-0224 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D703-0224
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D703-0224
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D703-0224 available by request