D715-0197 Screening compound: (10AS)-2-[4-(METHYLSULFANYL)PHENYL]-10,10A-DIHYDROIMIDAZO[1,5-B]ISOQUINOLINE-1,3(2H,5H)-DIONE

D715-0197 Screening compound: (10AS)-2-[4-(METHYLSULFANYL)PHENYL]-10,10A-DIHYDROIMIDAZO[1,5-B]ISOQUINOLINE-1,3(2H,5H)-DIONE
D715-0197 Screening compound: (10AS)-2-[4-(METHYLSULFANYL)PHENYL]-10,10A-DIHYDROIMIDAZO[1,5-B]ISOQUINOLINE-1,3(2H,5H)-DIONE alternative view

Chemical Structure Depiction of ChemDiv screening compound D715-0197
(10AS)-2-[4-(METHYLSULFANYL)PHENYL]-10,10A-DIHYDROIMIDAZO[1,5-B]ISOQUINOLINE-1,3(2H,5H)-DIONE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D715-0197

Molecular Formula

C18H16N2O2S (C18 H16 N2 O2 S)

Compound Name

(10AS)-2-[4-(METHYLSULFANYL)PHENYL]-10,10A-DIHYDROIMIDAZO[1,5-B]ISOQUINOLINE-1,3(2H,5H)-DIONE

IUPAC name

n/a

SMILES

CSc(cc1)ccc1N(C(C(C1)N2Cc3c1cccc3)=O)C2=O

InChI

InChI=1S/C18H16N2O2S/c1-23-15-8-6-14(7-9-15)20-17(21)16-10-12-4-2-3-5-13(12)11-19(16)18(20)22/h2-9,16H,10-11H2,1H3/t16-/m1/s1

InChI Key

WKZWBRNWVXVNCR-MRXNPFEDSA-N

MDL Number (MFCD)

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

324.4

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

3.465

Distribution Coefficient, logD

3.465

Water Solubility, LogSw

-3.61

Polar Surface Area

32.007

Acid Dissociation Constant (pKa)

12.06

Base Dissociation Constant (pKb)

-7.45

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

22.20

D715-0197 in Drug Discovery

Included in Screening Libraries

3D Mimetics PPI Library (1617 compounds)

Allosteric Kinases Inhibitors Library (23117 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

Targeted Diversity Library (40567 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Structure:
  • Mimetics
  • 3D
  • Mimetics
Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators
  • PPI modulators

References: we are preparing a list of scientific research reports with D715-0197 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D715-0197?
Check Price and Availability of D715-0197, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D715-0197 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D715-0197
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D715-0197
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D715-0197 available by request