D718-0004 Screening compound: N-(4,5-diphenyl-1,3-oxazol-2-yl)-2-(thiophen-2-yl)acetamide

D718-0004 Screening compound: N-(4,5-diphenyl-1,3-oxazol-2-yl)-2-(thiophen-2-yl)acetamide
D718-0004 Screening compound: N-(4,5-diphenyl-1,3-oxazol-2-yl)-2-(thiophen-2-yl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D718-0004
N-(4,5-diphenyl-1,3-oxazol-2-yl)-2-(thiophen-2-yl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D718-0004

Molecular Formula

C21H16N2O2S (C21 H16 N2 O2 S)

Compound Name

N-(4,5-diphenyl-1,3-oxazol-2-yl)-2-(thiophen-2-yl)acetamide

IUPAC name

N-(45-diphenyl-13-oxazol-2-yl)-2-(thiophen-2-yl)acetamide

SMILES

O=C(Cc1cccs1)Nc1nc(-c2ccccc2)c(-c2ccccc2)o1

InChI

InChI=1S/C21H16N2O2S/c24-18(14-17-12-7-13-26-17)22-21-23-19(15-8-3-1-4-9-15)20(25-21)16-10-5-2-6-11-16/h1-13H,14H2,(H,22,23,24)

InChI Key

CQATWWRVWUXSDP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD03300431

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

360.44

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

4.290

Distribution Coefficient, logD

4.290

Water Solubility, LogSw

-4.37

Polar Surface Area

43.381

Acid Dissociation Constant (pKa)

12.28

Base Dissociation Constant (pKb)

-0.42

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

4.80

D718-0004 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Cardiovascular Library (22201 compounds)

GPCR Targeted Library (31838 compounds)

Epitranscriptome Focused Small Molecule Library (20952 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cardiovascular
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • GPCR
  • Phosphatases
Mechanism of action:
  • Receptor's ligands
  • Epigenetic

References: we are preparing a list of scientific research reports with D718-0004 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D718-0004?
Check Price and Availability of D718-0004, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D718-0004 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D718-0004
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D718-0004
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D718-0004 available by request