D718-1142 Screening compound: 6-(4-methoxyphenyl)-5-methyl-2-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyrimidin-7-amine

D718-1142 Screening compound: 6-(4-methoxyphenyl)-5-methyl-2-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyrimidin-7-amine
D718-1142 Screening compound: 6-(4-methoxyphenyl)-5-methyl-2-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyrimidin-7-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound D718-1142
6-(4-methoxyphenyl)-5-methyl-2-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyrimidin-7-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D718-1142

Molecular Formula

C14H12F3N5O (C14 H12 F3 N5 O)

Compound Name

6-(4-methoxyphenyl)-5-methyl-2-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyrimidin-7-amine

IUPAC name

6-(4-methoxyphenyl)-5-methyl-2-(trifluoromethyl)-[124]triazolo[15-a]pyrimidin-7-amine

SMILES

Cc1nc2nc(C(F)(F)F)nn2c(N)c1-c(cc1)ccc1OC

InChI

InChI=1S/C14H12F3N5O/c1-7-10(8-3-5-9(23-2)6-4-8)11(18)22-13(19-7)20-12(21-22)14(15,16)17/h3-6H,18H2,1-2H3

InChI Key

PGUAHPVOYKRRDM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD09463624

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

323.28

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.524

Distribution Coefficient, logD

2.523

Water Solubility, LogSw

-2.61

Polar Surface Area

57.899

Acid Dissociation Constant (pKa)

17.12

Base Dissociation Constant (pKb)

4.07

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

21.43

D718-1142 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

Antimitotic Tubulin Library (17355 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin

References: we are preparing a list of scientific research reports with D718-1142 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D718-1142?
Check Price and Availability of D718-1142, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D718-1142 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D718-1142
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D718-1142
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D718-1142 available by request