D718-1377 Screening compound: 7-(4-hydroxy-3-methoxyphenyl)-2-methyl-4H,7H-[1,2,4]triazolo[1,5-a]pyrimidine-5-carboxylic acid

D718-1377 Screening compound: 7-(4-hydroxy-3-methoxyphenyl)-2-methyl-4H,7H-[1,2,4]triazolo[1,5-a]pyrimidine-5-carboxylic acid
D718-1377 Screening compound: 7-(4-hydroxy-3-methoxyphenyl)-2-methyl-4H,7H-[1,2,4]triazolo[1,5-a]pyrimidine-5-carboxylic acid alternative view

Chemical Structure Depiction of ChemDiv screening compound D718-1377
7-(4-hydroxy-3-methoxyphenyl)-2-methyl-4H,7H-[1,2,4]triazolo[1,5-a]pyrimidine-5-carboxylic acid

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D718-1377

Molecular Formula

C14H14N4O4 (C14 H14 N4 O4)

Compound Name

7-(4-hydroxy-3-methoxyphenyl)-2-methyl-4H,7H-[1,2,4]triazolo[1,5-a]pyrimidine-5-carboxylic acid

IUPAC name

7-(4-hydroxy-3-methoxyphenyl)-2-methyl-4H7H-[124]triazolo[15-a]pyrimidine-5-carboxylic acid

SMILES

Cc1nn(C(C=C(C(O)=O)N2)c(cc3)cc(OC)c3O)c2n1

InChI

InChI=1S/C14H14N4O4/c1-7-15-14-16-9(13(20)21)6-10(18(14)17-7)8-3-4-11(19)12(5-8)22-2/h3-6,10,19H,1-2H3,(H,20,21)(H,15,16,17)/t10-/m1/s1

InChI Key

LIUGCFGVAQSTOG-SNVBAGLBSA-N

MDL Number (MFCD)

MFCD11082397

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

302.29

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

0.636

Distribution Coefficient, logD

-3.003

Water Solubility, LogSw

-1.92

Polar Surface Area

90.130

Acid Dissociation Constant (pKa)

3.76

Base Dissociation Constant (pKb)

-0.02

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

21.40

D718-1377 in Drug Discovery

Included in Screening Libraries

Anti-Inflammatory Library (24602 compounds)

Antiviral HBV Library (10007 compounds)

Antiviral Library (67538 compounds)

BRD4 Targeted Library (4534 compounds)

RNA-Protein Interaction Inhibitors Library (1986 compounds)

Antibacterial Compounds Library (13827 compounds)

Carbonic Anhydrase II Library (4939 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Antiviral
  • Infections
  • Immune system
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Hemic and lymphatic
  • Cardiovascular
  • Metabolic
  • Infections
  • Immune system
  • animal
Targets:
  • Others

References: we are preparing a list of scientific research reports with D718-1377 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D718-1377?
Check Price and Availability of D718-1377, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D718-1377 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D718-1377
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D718-1377
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D718-1377 available by request