D718-1601 Screening compound: methyl 2-methyl-5-oxo-6-(4-phenyl-1,3-thiazol-2-yl)-5,6-dihydro-1,6-naphthyridine-3-carboxylate

D718-1601 Screening compound: methyl 2-methyl-5-oxo-6-(4-phenyl-1,3-thiazol-2-yl)-5,6-dihydro-1,6-naphthyridine-3-carboxylate
D718-1601 Screening compound: methyl 2-methyl-5-oxo-6-(4-phenyl-1,3-thiazol-2-yl)-5,6-dihydro-1,6-naphthyridine-3-carboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound D718-1601
methyl 2-methyl-5-oxo-6-(4-phenyl-1,3-thiazol-2-yl)-5,6-dihydro-1,6-naphthyridine-3-carboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D718-1601

Molecular Formula

C20H15N3O3S (C20 H15 N3 O3 S)

Compound Name

methyl 2-methyl-5-oxo-6-(4-phenyl-1,3-thiazol-2-yl)-5,6-dihydro-1,6-naphthyridine-3-carboxylate

IUPAC name

methyl 2-methyl-5-oxo-6-(4-phenyl-13-thiazol-2-yl)-56-dihydro-16-naphthyridine-3-carboxylate

SMILES

Cc(c(C(OC)=O)c1)nc(C=CN2c3nc(-c4ccccc4)cs3)c1C2=O

InChI

InChI=1S/C20H15N3O3S/c1-12-14(19(25)26-2)10-15-16(21-12)8-9-23(18(15)24)20-22-17(11-27-20)13-6-4-3-5-7-13/h3-11H,1-2H3

InChI Key

LJDDYIVKCCVHHD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD11082537

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

377.42

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.454

Distribution Coefficient, logD

4.454

Water Solubility, LogSw

-4.55

Polar Surface Area

56.652

Acid Dissociation Constant (pKa)

28.51

Base Dissociation Constant (pKb)

1.00

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

10.00

D718-1601 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

SmartTM Library (51161 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Kinases
  • Proteases

References: we are preparing a list of scientific research reports with D718-1601 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D718-1601?
Check Price and Availability of D718-1601, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D718-1601 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D718-1601
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D718-1601
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D718-1601 available by request