D718-1645 Screening compound: 2-{2-ethyl-5-oxo-4H,5H,6H-imidazo[1,2-b][1,2,4]triazol-6-yl}-N-(2-methoxyphenyl)acetamide

D718-1645 Screening compound: 2-{2-ethyl-5-oxo-4H,5H,6H-imidazo[1,2-b][1,2,4]triazol-6-yl}-N-(2-methoxyphenyl)acetamide
D718-1645 Screening compound: 2-{2-ethyl-5-oxo-4H,5H,6H-imidazo[1,2-b][1,2,4]triazol-6-yl}-N-(2-methoxyphenyl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D718-1645
2-{2-ethyl-5-oxo-4H,5H,6H-imidazo[1,2-b][1,2,4]triazol-6-yl}-N-(2-methoxyphenyl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D718-1645

Molecular Formula

C15H17N5O3 (C15 H17 N5 O3)

Compound Name

2-{2-ethyl-5-oxo-4H,5H,6H-imidazo[1,2-b][1,2,4]triazol-6-yl}-N-(2-methoxyphenyl)acetamide

IUPAC name

2-{2-ethyl-5-oxo-4H5H6H-imidazo[12-b][124]triazol-6-yl}-N-(2-methoxyphenyl)acetamide

SMILES

CCc1nn(C(CC(Nc(cccc2)c2OC)=O)C(N2)=O)c2n1

InChI

InChI=1S/C15H17N5O3/c1-3-12-17-15-18-14(22)10(20(15)19-12)8-13(21)16-9-6-4-5-7-11(9)23-2/h4-7,10H,3,8H2,1-2H3,(H,16,21)(H,17,18,19,22)/t10-/m0/s1

InChI Key

DPSPNVONFZPGLR-JTQLQIEISA-N

MDL Number (MFCD)

MFCD12212255

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

315.33

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

0.986

Distribution Coefficient, logD

0.957

Water Solubility, LogSw

-2.08

Polar Surface Area

82.582

Acid Dissociation Constant (pKa)

8.55

Base Dissociation Constant (pKb)

2.00

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

33.30

D718-1645 in Drug Discovery

Included in Screening Libraries

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with D718-1645 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D718-1645?
Check Price and Availability of D718-1645, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D718-1645 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D718-1645
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D718-1645
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D718-1645 available by request