D718-1786 Screening compound: N~1~-(1-naphthyl)-2-(2-oxo-2,3-dihydro-1H-imidazo[1,2-a][1,3]benzimidazol-3-yl)acetamide

D718-1786 Screening compound: N~1~-(1-naphthyl)-2-(2-oxo-2,3-dihydro-1H-imidazo[1,2-a][1,3]benzimidazol-3-yl)acetamide
D718-1786 Screening compound: N~1~-(1-naphthyl)-2-(2-oxo-2,3-dihydro-1H-imidazo[1,2-a][1,3]benzimidazol-3-yl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D718-1786
N~1~-(1-naphthyl)-2-(2-oxo-2,3-dihydro-1H-imidazo[1,2-a][1,3]benzimidazol-3-yl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D718-1786

Molecular Formula

C21H16N4O2 (C21 H16 N4 O2)

Compound Name

N~1~-(1-naphthyl)-2-(2-oxo-2,3-dihydro-1H-imidazo[1,2-a][1,3]benzimidazol-3-yl)acetamide

IUPAC name

N-(naphthalen-1-yl)-2-{4-oxo-257-triazatricyclo[6.4.0.0^{26}]dodeca-1(12)6810-tetraen-3-yl}acetamide

SMILES

O=C(CC(C(N1)=O)n2c1nc1c2cccc1)Nc1cccc2ccccc12

InChI

InChI=1S/C21H16N4O2/c26-19(22-15-10-5-7-13-6-1-2-8-14(13)15)12-18-20(27)24-21-23-16-9-3-4-11-17(16)25(18)21/h1-11,18H,12H2,(H,22,26)(H,23,24,27)/t18-/m0/s1

InChI Key

SSTJFJFLIJFZHP-SFHVURJKSA-N

MDL Number (MFCD)

MFCD11852670

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

356.38

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.829

Distribution Coefficient, logD

2.822

Water Solubility, LogSw

-3.23

Polar Surface Area

60.674

Acid Dissociation Constant (pKa)

9.22

Base Dissociation Constant (pKb)

4.55

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

9.50

D718-1786 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS Targets (44014 compounds)

DGK Inhibitors Library (10558 compounds)

Nucleic Acid Ligands (8311 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cancer
  • Digestive system
  • Hemic and lymphatic
  • Skin
  • Metabolic
  • Immune system
  • Infections
  • Cancer
  • Musculoskeletal
  • Nervous system
  • Hemic and lymphatic
  • Immune system
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with D718-1786 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D718-1786?
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What is the minimum amount of D718-1786 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D718-1786
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D718-1786
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D718-1786 available by request