D724-0200 Screening compound: 5-[3-(3,4-dimethylanilino)-2-hydroxypropyl]-3-methyl-1-oxo-1,5-dihydropyrido[1,2-a][1,3]benzimidazol-4-yl cyanide

D724-0200 Screening compound: 5-[3-(3,4-dimethylanilino)-2-hydroxypropyl]-3-methyl-1-oxo-1,5-dihydropyrido[1,2-a][1,3]benzimidazol-4-yl cyanide
D724-0200 Screening compound: 5-[3-(3,4-dimethylanilino)-2-hydroxypropyl]-3-methyl-1-oxo-1,5-dihydropyrido[1,2-a][1,3]benzimidazol-4-yl cyanide alternative view

Chemical Structure Depiction of ChemDiv screening compound D724-0200
5-[3-(3,4-dimethylanilino)-2-hydroxypropyl]-3-methyl-1-oxo-1,5-dihydropyrido[1,2-a][1,3]benzimidazol-4-yl cyanide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D724-0200

Molecular Formula

C24H24N4O2 (C24 H24 N4 O2)

Compound Name

5-[3-(3,4-dimethylanilino)-2-hydroxypropyl]-3-methyl-1-oxo-1,5-dihydropyrido[1,2-a][1,3]benzimidazol-4-yl cyanide

IUPAC name

8-{3-[(34-dimethylphenyl)amino]-2-hydroxypropyl}-11-methyl-13-oxo-18-diazatricyclo[7.4.0.0^{27}]trideca-246911-pentaene-10-carbonitrile

SMILES

Cc(cc1)c(C)cc1NCC(CN(c(cccc1)c1N1C(C=C2C)=O)C1=C2C#N)O

InChI

InChI=1S/C24H24N4O2/c1-15-8-9-18(10-16(15)2)26-13-19(29)14-27-21-6-4-5-7-22(21)28-23(30)11-17(3)20(12-25)24(27)28/h4-11,19,26,29H,13-14H2,1-3H3/t19-/m0/s1

InChI Key

XIWYAZCGOWXVCJ-IBGZPJMESA-N

MDL Number (MFCD)

MFCD05705545

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

400.48

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.572

Distribution Coefficient, logD

3.572

Water Solubility, LogSw

-3.70

Polar Surface Area

61.784

Acid Dissociation Constant (pKa)

16.48

Base Dissociation Constant (pKb)

3.26

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

25.00

D724-0200 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

DGK Inhibitors Library (10558 compounds)

Regenerative Medicine Focused Library (23016 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Hemic and lymphatic
  • Skin
  • Metabolic
  • Immune system
  • Musculoskeletal
  • Digestive system
  • Hemic and lymphatic
  • Cardiovascular
  • Skin
  • wounds
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with D724-0200 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D724-0200?
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What is the minimum amount of D724-0200 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D724-0200
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D724-0200
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D724-0200 available by request